Transient myeloproliferative disorders can be associated with hydrops in Down syndrome fetuses. No cases of prenatal management of such a condition have been reported in the literature. We report a case of myeloproliferative disorder diagnosed by cordocentesis at 31 weeks in a Down syndrome fetus with pericardial effusion. A pericardiocentesis was performed at the first signs of hydrops and successfully improved fetal cardiac function, allowing for continuation of pregnancy.
Strobelt, N., Ghidini, A., Locatelli, A., Vergani, P., Mariani, S., Biondi, A. (1995). Intrauterine diagnosis and management of transient myeloproliferative disorder. AMERICAN JOURNAL OF PERINATOLOGY, 12(2), 132-134 [10.1055/s-2007-994424].
Intrauterine diagnosis and management of transient myeloproliferative disorder
LOCATELLI, ANNA;VERGANI, PATRIZIA;BIONDI, ANDREA
1995
Abstract
Transient myeloproliferative disorders can be associated with hydrops in Down syndrome fetuses. No cases of prenatal management of such a condition have been reported in the literature. We report a case of myeloproliferative disorder diagnosed by cordocentesis at 31 weeks in a Down syndrome fetus with pericardial effusion. A pericardiocentesis was performed at the first signs of hydrops and successfully improved fetal cardiac function, allowing for continuation of pregnancy.
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