Background and Aims: Liver disease (LD) is a major cause of morbidity and mortality worldwide. Development of outcome indicators (OIs) provides health care policy makers with objective criteria that can be used to generate a virtuous competition to improve value of care. Aim of our study was to generate and test a set of health care OIs for the major LDs. Methods: Using a modified Delphi method, 7 expert panels identified a set of OIs according to experience and scientific evidence (as of 2010). Each OI was rated in a two-step process using the RAND 9-point agreement scale. Median scores were computed for each OI. After the second rating, a disagreement index (DI) was calculated to identify and accept (if DI≤1) OIs with median rating ≥7. The final set of selected OIs was tested through an ongoing prospective multicenter observational study involving three tertiary centers in Lombardy, Italy. Results: A total of 51 OIs were identified by the focus groups. We recruited 3213 consecutive liver patients, of whom 91% had at least one follow-up visit after a median follow-up time of 15 months. Among these patients, 1752 were cirrhotic and 711 were affected by HCC. During observation time, 156 patients were transplanted and 210 patients died. All the identified OIs were successfully tested in the clinical setting showing excellent performance and correlation with natural history information. Conclusions: This study provides a set of validated outcomes indicators that can be used to monitor the performance of referral centers and improve the value and sustainability of care.
Rota, M., Okolicsanyi, S., Ciaccio, A., Gemma, M., Gentiluomo, M., Grisolia, A., et al. (2014). Generation and performance of value-based outcome indicators in liver disease: The multicenter V.B.M.H. study. JOURNAL OF HEPATOLOGY, 60(1, Supplement), 517-517 [10.1016/S0168-8278(14)61440-9].
|Citazione:||Rota, M., Okolicsanyi, S., Ciaccio, A., Gemma, M., Gentiluomo, M., Grisolia, A., et al. (2014). Generation and performance of value-based outcome indicators in liver disease: The multicenter V.B.M.H. study. JOURNAL OF HEPATOLOGY, 60(1, Supplement), 517-517 [10.1016/S0168-8278(14)61440-9].|
|Tipo:||Abstract in rivista|
|Carattere della pubblicazione:||Scientifica|
|Presenza di un coautore afferente ad Istituzioni straniere:||No|
|Titolo:||Generation and performance of value-based outcome indicators in liver disease: The multicenter V.B.M.H. study|
|Autori:||Rota, M; Okolicsanyi, S; Ciaccio, A; Gemma, M; Gentiluomo, M; Grisolia, A; Cortesi, P; Scalone, L; Mantovani, L; Cesana, G; Valsecchi, M; Pontisso, P; Mondelli, M; Marchesini, G; Fabris, L; Mazzaferro, V; Burra, P; Colledan, M; Fagiuoli, S; Belli, L; Strazzabosco, M|
|Data di pubblicazione:||apr-2014|
|Rivista:||JOURNAL OF HEPATOLOGY|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1016/S0168-8278(14)61440-9|
|Appare nelle tipologie:||01 - Articolo su rivista|