Supplemental oxygen (hyperoxia) improves physical performance during hypoxic exercise. Based on the analysis of metabolome and iron homeostasis from human athlete blood samples, we show that hyperoxia during recovery periods interferes with metabolic alterations following hypoxic exercise. This may impair beneficial adaptations to exercise and/or hypoxia and highlights risks of oxygen supplementation in hypoxia.
Burtscher, J., Paglia, G., Denti, V., Faulhaber, M., Weiss, G., Schobersberger, W., et al. (2024). Hyperoxic recovery interferes with the metabolic imprint of hypoxic exercise. FREE RADICAL BIOLOGY & MEDICINE, 223(October 2024), 193-198 [10.1016/j.freeradbiomed.2024.07.024].
Hyperoxic recovery interferes with the metabolic imprint of hypoxic exercise
Paglia G.;Denti V.;
2024
Abstract
Supplemental oxygen (hyperoxia) improves physical performance during hypoxic exercise. Based on the analysis of metabolome and iron homeostasis from human athlete blood samples, we show that hyperoxia during recovery periods interferes with metabolic alterations following hypoxic exercise. This may impair beneficial adaptations to exercise and/or hypoxia and highlights risks of oxygen supplementation in hypoxia.
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