PAMELA (Pressioni Arteriose Monitorate E Loro Associazioni) is an epidemiological study, originally designed to determine the normality of home and ambulatory blood pressure values. The study was performed on 3,200 subjects, aged 25 to 74 years, randomly selected from the general population of Monza (Milan, Italy). In the study context we performed clinical, home and ambulatory blood pressure measurements, echocardiographic assessment of cardiac structure and function as well as laboratory examinations (glucose and lipids). Personal and family histories were collected. The same procedures were repeated 10 years later. During a 12-year follow-up, the incident cardiovascular events were validated. Cardiovascular and all-cause fatal events were collected for a 16-year follow-up. This article will review the main results of the PAMELA study, with particular emphasis on (1) the prognostic value of the different blood pressure measurements, (2) the relationships between metabolic variables and blood pressure and (3) the clinical relevance and prognostic importance of left ventricular mass values and alterations.

Bombelli, M., Toso, E., Peronio, M., Fodri, D., Volpe, M., Brambilla, G., et al. (2013). The Pamela study: main findings and perspectives. CURRENT HYPERTENSION REPORTS, 15(3), 238-243 [10.1007/s11906-013-0348-1].

The Pamela study: main findings and perspectives

BOMBELLI, MICHELE;TOSO, ELENA;PERONIO, MARIA;FODRI, DANILO;VOLPE, MARCO ANTONIO VALENTINO;BRAMBILLA, GIANMARIA;FACCHETTI, RITA LUCIA;SEGA, ROBERTO;GRASSI, GUIDO;MANCIA, GIUSEPPE
2013

Abstract

PAMELA (Pressioni Arteriose Monitorate E Loro Associazioni) is an epidemiological study, originally designed to determine the normality of home and ambulatory blood pressure values. The study was performed on 3,200 subjects, aged 25 to 74 years, randomly selected from the general population of Monza (Milan, Italy). In the study context we performed clinical, home and ambulatory blood pressure measurements, echocardiographic assessment of cardiac structure and function as well as laboratory examinations (glucose and lipids). Personal and family histories were collected. The same procedures were repeated 10 years later. During a 12-year follow-up, the incident cardiovascular events were validated. Cardiovascular and all-cause fatal events were collected for a 16-year follow-up. This article will review the main results of the PAMELA study, with particular emphasis on (1) the prognostic value of the different blood pressure measurements, (2) the relationships between metabolic variables and blood pressure and (3) the clinical relevance and prognostic importance of left ventricular mass values and alterations.
Articolo in rivista - Review Essay
Blood Pressure; Humans; Blood Pressure Determination; Prognosis; Italy; Hypertension; Blood Glucose
English
238
243
6
Bombelli, M., Toso, E., Peronio, M., Fodri, D., Volpe, M., Brambilla, G., et al. (2013). The Pamela study: main findings and perspectives. CURRENT HYPERTENSION REPORTS, 15(3), 238-243 [10.1007/s11906-013-0348-1].
Bombelli, M; Toso, E; Peronio, M; Fodri, D; Volpe, M; Brambilla, G; Facchetti, R; Sega, R; Grassi, G; Mancia, G
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/49675
Citazioni
  • Scopus 17
  • ???jsp.display-item.citation.isi??? 17
Social impact