Objective: Different etiologies for early- (<34.0 weeks) and late (34.0 weeks)-onset preeclampsia (EO-LO PE) are reported. The aim of our study is to identify influencing factors for the LO form. Methods: Retrospective study of 284 consecutive women diagnosed as preeclamptic at 22.4-41.5 weeks, from 3/2005 to 10/2011, evaluated in relation to EO versus LO PE. Results: LO PE was identified in 151 cases. Gestational Diabetes Mellitus (11% versus 4%, p=0.04), body mass index (BMI) 35kg/m (9% versus 2%, p=0.03), pathological weight gain for BMI class (30% versus 13%, p=0.001), 5 (58% versus 23%, p<0.001) and 7kg/m BMI increase (19% versus 9%, p=0.04) were more common in LO than in EO PE. At Estimation Regression analysis weighted for Gestational Age (GA) at delivery BMI 35 and 5kg/m BMI increase resulted related to LO PE (OR=3.76, CI(95%)=1.97-17.04; OR=4.28, CI(95%)=2.44-7.54). Conclusions: BMI 35 and 5kg/m increase appeared as influencing factors for LO PE, thus supporting the role of systemic inflammation in its pathogenesis. © 2013 Informa UK Ltd. All rights reserved: reproduction in whole or part not permitted.

Ornaghi, S., Tyurmorezova, A., Algeri, P., Giardini, V., Ceruti, P., Vertemati, E., et al. (2013). Influencing factors for late-onset preeclampsia. THE JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE, 26(13), 1299-1302 [10.3109/14767058.2013.783807].

Influencing factors for late-onset preeclampsia

ORNAGHI, SARA;GIARDINI, VALENTINA;VERGANI, PATRIZIA
2013

Abstract

Objective: Different etiologies for early- (<34.0 weeks) and late (34.0 weeks)-onset preeclampsia (EO-LO PE) are reported. The aim of our study is to identify influencing factors for the LO form. Methods: Retrospective study of 284 consecutive women diagnosed as preeclamptic at 22.4-41.5 weeks, from 3/2005 to 10/2011, evaluated in relation to EO versus LO PE. Results: LO PE was identified in 151 cases. Gestational Diabetes Mellitus (11% versus 4%, p=0.04), body mass index (BMI) 35kg/m (9% versus 2%, p=0.03), pathological weight gain for BMI class (30% versus 13%, p=0.001), 5 (58% versus 23%, p<0.001) and 7kg/m BMI increase (19% versus 9%, p=0.04) were more common in LO than in EO PE. At Estimation Regression analysis weighted for Gestational Age (GA) at delivery BMI 35 and 5kg/m BMI increase resulted related to LO PE (OR=3.76, CI(95%)=1.97-17.04; OR=4.28, CI(95%)=2.44-7.54). Conclusions: BMI 35 and 5kg/m increase appeared as influencing factors for LO PE, thus supporting the role of systemic inflammation in its pathogenesis. © 2013 Informa UK Ltd. All rights reserved: reproduction in whole or part not permitted.
Articolo in rivista - Articolo scientifico
preeclampsia
English
2013
26
13
1299
1302
none
Ornaghi, S., Tyurmorezova, A., Algeri, P., Giardini, V., Ceruti, P., Vertemati, E., et al. (2013). Influencing factors for late-onset preeclampsia. THE JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE, 26(13), 1299-1302 [10.3109/14767058.2013.783807].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/49186
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