The prognosis of malignant gliomas remains largely unsatisfactory for the intrinsic characteristics of the pathology and for the delayed diagnosis. Multimodal imaging based on PET and MRI may assess the dynamics of disease onset and progression allowing the validation of preclinical models of glioblastoma multiforme (GBM). The aim of this study was the characterization of a syngeneic rat model of GBM using combined in vivo imaging and immunohistochemistry.

Belloli, S., Brioschi, A., Politi, L., Ronchetti, F., Calderoni, S., Raccagni, I., et al. (2013). Characterization of biological features of a rat F98 GBM model: a PET-MRI study with [18F]FAZA and [18F]FDG. NUCLEAR MEDICINE AND BIOLOGY, 40(6), 831-840 [10.1016/j.nucmedbio.2013.05.004].

Characterization of biological features of a rat F98 GBM model: a PET-MRI study with [18F]FAZA and [18F]FDG

RACCAGNI, ISABELLA;FAZIO, FERRUCCIO;MORESCO, ROSA MARIA
2013

Abstract

The prognosis of malignant gliomas remains largely unsatisfactory for the intrinsic characteristics of the pathology and for the delayed diagnosis. Multimodal imaging based on PET and MRI may assess the dynamics of disease onset and progression allowing the validation of preclinical models of glioblastoma multiforme (GBM). The aim of this study was the characterization of a syngeneic rat model of GBM using combined in vivo imaging and immunohistochemistry.
Articolo in rivista - Articolo scientifico
MRI; Hypoxia; PET; Glucose metabolism; Immunohistochemistry; GBM model
English
ago-2013
831
840
10
Belloli, S., Brioschi, A., Politi, L., Ronchetti, F., Calderoni, S., Raccagni, I., et al. (2013). Characterization of biological features of a rat F98 GBM model: a PET-MRI study with [18F]FAZA and [18F]FDG. NUCLEAR MEDICINE AND BIOLOGY, 40(6), 831-840 [10.1016/j.nucmedbio.2013.05.004].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/48836
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