Positron emission tomography/computed tomography (PET/CT) with C-11 choline is currently used for restaging prostate cancer in patients with biochemical failure. Skeletal Paget disease can be associated with prostate cancer, and bone scintigraphy can differentiate the 2 conditions. We report the case of a 74-year-old patient with prostate cancer who displayed multiple areas skeletal uptake of C-11 choline on a restaging PET/CT, which was attributed to both metastatic and pagetic bone diseases. The pattern of C-11 choline uptake was different between the 2 conditions, probably in relation to the different mechanisms of disease. The possibility of C-11 choline uptake in pagetic bone should be kept in mind when interpreting PET/CT findings in patients with prostate cancer.

Giovacchini, G., Gajate, A., Messa, M., & Fazio, F. (2008). Increased C-11 choline uptake in pagetic bone in a patient with coexisting skeletal metastases from prostate cancer. CLINICAL NUCLEAR MEDICINE, 33(11), 797-798 [10.1097/RLU.0b013e318187ee35].

Increased C-11 choline uptake in pagetic bone in a patient with coexisting skeletal metastases from prostate cancer

MESSA, MARIA CRISTINA;FAZIO, FERRUCCIO
2008

Abstract

Positron emission tomography/computed tomography (PET/CT) with C-11 choline is currently used for restaging prostate cancer in patients with biochemical failure. Skeletal Paget disease can be associated with prostate cancer, and bone scintigraphy can differentiate the 2 conditions. We report the case of a 74-year-old patient with prostate cancer who displayed multiple areas skeletal uptake of C-11 choline on a restaging PET/CT, which was attributed to both metastatic and pagetic bone diseases. The pattern of C-11 choline uptake was different between the 2 conditions, probably in relation to the different mechanisms of disease. The possibility of C-11 choline uptake in pagetic bone should be kept in mind when interpreting PET/CT findings in patients with prostate cancer.
No
Articolo in rivista - Articolo scientifico
Scientifica
C-11choline, Paget disease, prostate cancer, PET/CT
English
797
798
2
Giovacchini, G., Gajate, A., Messa, M., & Fazio, F. (2008). Increased C-11 choline uptake in pagetic bone in a patient with coexisting skeletal metastases from prostate cancer. CLINICAL NUCLEAR MEDICINE, 33(11), 797-798 [10.1097/RLU.0b013e318187ee35].
Giovacchini, G; Gajate, A; Messa, M; Fazio, F
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10281/4832
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