The current prospective, multicenter study sought to identify single nucleotide polymorphisms of voltage-gated sodium channels (SCNAs) genes that might confer susceptibility to an increased incidence and severity of oxaliplatin-induced peripheral neuropathy (OXAIPN) in patients treated with either leucovorin, 5-fluorouracil, and oxaliplatin (FOLFOX) or oxaliplatin plus capecitabine (XELOX) for colorectal cancer (CRC)

Argyriou, A., Cavaletti, G., Antonacopoulou, A., Genazzani, A., Briani, C., Bruna, J., et al. (2013). Voltage-gated sodium channel polymorphisms play a pivotal role in the development of oxaliplatin-induced peripheral neurotoxicity: Results from a prospective multicenter study. CANCER, 119(19), 3570-3577 [10.1002/cncr.28234].

Voltage-gated sodium channel polymorphisms play a pivotal role in the development of oxaliplatin-induced peripheral neurotoxicity: Results from a prospective multicenter study

Cavaletti, G;Alberti, P;Cortinovis, D;Cazzaniga, ME;
2013

Abstract

The current prospective, multicenter study sought to identify single nucleotide polymorphisms of voltage-gated sodium channels (SCNAs) genes that might confer susceptibility to an increased incidence and severity of oxaliplatin-induced peripheral neuropathy (OXAIPN) in patients treated with either leucovorin, 5-fluorouracil, and oxaliplatin (FOLFOX) or oxaliplatin plus capecitabine (XELOX) for colorectal cancer (CRC)
Articolo in rivista - Articolo scientifico
Scientifica
neurotoxicity; genotyping; chemotherapy-induced peripheral neuropathy; oxaliplatin; biomarkers; SCNA
English
Argyriou, A., Cavaletti, G., Antonacopoulou, A., Genazzani, A., Briani, C., Bruna, J., et al. (2013). Voltage-gated sodium channel polymorphisms play a pivotal role in the development of oxaliplatin-induced peripheral neurotoxicity: Results from a prospective multicenter study. CANCER, 119(19), 3570-3577 [10.1002/cncr.28234].
Argyriou, A; Cavaletti, G; Antonacopoulou, A; Genazzani, A; Briani, C; Bruna, J; Terrazzino, S; Velasco, R; Alberti, P; Campagnolo, M; Lonardi, S; Cortinovis, D; Cazzaniga, M; Santos, C; Psaromyalou, A; Angelopoulou, A; Kalofonos, H
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10281/47412
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