Left ventricular hypertrophy (LVH) is a cardinal manifestation of organ damage in patients with arterial hypertension. Identifying LVH is a fundamental step in evaluating hypertensive patients, because clinical and epidemiologic studies have shown this condition has a strong independent adverse prognostic significance. LVH is an integrated marker of cardiovascular risk, reflecting hypertension's hemodynamic and nonhemodynamic effects on the heart. Reversing LVH is an intermediate goal of antihypertensive therapy. Pharmacologic strategies to reverse LVH should be based on combining two or more drugs: a renin-angiotensin system blocker (ie, angiotensin-converting enzyme inhibitor or angiotensin receptor antagonist), and a calcium antagonist or low-dose diuretic. Successful therapeutic plans should also include nonpharmacologic interventions to promote LVH regression.

Cuspidi, C., Sala, C., & Zanchetti, A. (2007). Management of hypertension in patients with left ventricular hypertrophy. CURRENT HYPERTENSION REPORTS, 9(6), 498-505 [10.1007/s11906-007-0091-6].

Management of hypertension in patients with left ventricular hypertrophy

CUSPIDI, CESARE;
2007-12

Abstract

Left ventricular hypertrophy (LVH) is a cardinal manifestation of organ damage in patients with arterial hypertension. Identifying LVH is a fundamental step in evaluating hypertensive patients, because clinical and epidemiologic studies have shown this condition has a strong independent adverse prognostic significance. LVH is an integrated marker of cardiovascular risk, reflecting hypertension's hemodynamic and nonhemodynamic effects on the heart. Reversing LVH is an intermediate goal of antihypertensive therapy. Pharmacologic strategies to reverse LVH should be based on combining two or more drugs: a renin-angiotensin system blocker (ie, angiotensin-converting enzyme inhibitor or angiotensin receptor antagonist), and a calcium antagonist or low-dose diuretic. Successful therapeutic plans should also include nonpharmacologic interventions to promote LVH regression.
Articolo in rivista - Articolo scientifico
Scientifica
left ventricular hypertrophy,left ventricular regression, hypertension
English
498
505
Cuspidi, C., Sala, C., & Zanchetti, A. (2007). Management of hypertension in patients with left ventricular hypertrophy. CURRENT HYPERTENSION REPORTS, 9(6), 498-505 [10.1007/s11906-007-0091-6].
Cuspidi, C; Sala, C; Zanchetti, A
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10281/4715
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