Purpose: To report procedural data and outcomes of a novel image guidance technique, CT renal arteriography (CTRA), performed to target and ablate small intraparenchymal renal tumors. Materials and methods: We retrospectively analyzed data of 2 patients undergoing CTRA-guided ablation for 3 renal intraparenchymal tumors, from February to March 2023. We previously evaluated tumor visibility with US/CEUS, and in all cases conspicuity was poor, whereas contrast-enhanced CT (CECT) clearly depicted all hypervascular nodules. Our primary endpoint was CTRA-guidance feasibility for renal ablation, defined as the precise probe deployment inside the target tumor. The secondary endpoint was CTRA-guided ablation technical success, intended as the inclusion of the whole tumor inside the necrotic volume, with 5 mm safety margins. RENAL scores, complications, procedural time, dose length product (DLP), serum creatinine variation and hospital stay length were also recorded. Results: A confident deployment of the probe tip inside the nodule was accomplished in all 3 cases, with a 100% of correct targeting. We observed immediate technical success after all 3 ablations. The 3 nodules had a RENAL score <7 points, and we encountered no complications due to line placement or ablation. The average time from preablative to postablative CTRA was 54 min (50–58min), with a DLP of 3632mGy*cm (2807–4458mGy*cm). Serum creatinine didn’t show a significant variation after the procedures; both patients were hospitalized for 2 days. Conclusion: Preliminary data showed that CTRA-guidance might provide unique advantages over conventional CECT-guidance to assist the ablation of small renal intraparenchymal tumor not visualized on US/CEUS.

Muglia, R., Marra, P., Dulcetta, L., Carbone, F., Sironi, S. (2023). CT renal arteriography as a novel imaging guidance for the percutaneous ablation of small renal tumors. INTERNATIONAL JOURNAL OF HYPERTHERMIA, 40(1) [10.1080/02656736.2023.2244706].

CT renal arteriography as a novel imaging guidance for the percutaneous ablation of small renal tumors

Marra P.;Sironi S.
2023

Abstract

Purpose: To report procedural data and outcomes of a novel image guidance technique, CT renal arteriography (CTRA), performed to target and ablate small intraparenchymal renal tumors. Materials and methods: We retrospectively analyzed data of 2 patients undergoing CTRA-guided ablation for 3 renal intraparenchymal tumors, from February to March 2023. We previously evaluated tumor visibility with US/CEUS, and in all cases conspicuity was poor, whereas contrast-enhanced CT (CECT) clearly depicted all hypervascular nodules. Our primary endpoint was CTRA-guidance feasibility for renal ablation, defined as the precise probe deployment inside the target tumor. The secondary endpoint was CTRA-guided ablation technical success, intended as the inclusion of the whole tumor inside the necrotic volume, with 5 mm safety margins. RENAL scores, complications, procedural time, dose length product (DLP), serum creatinine variation and hospital stay length were also recorded. Results: A confident deployment of the probe tip inside the nodule was accomplished in all 3 cases, with a 100% of correct targeting. We observed immediate technical success after all 3 ablations. The 3 nodules had a RENAL score <7 points, and we encountered no complications due to line placement or ablation. The average time from preablative to postablative CTRA was 54 min (50–58min), with a DLP of 3632mGy*cm (2807–4458mGy*cm). Serum creatinine didn’t show a significant variation after the procedures; both patients were hospitalized for 2 days. Conclusion: Preliminary data showed that CTRA-guidance might provide unique advantages over conventional CECT-guidance to assist the ablation of small renal intraparenchymal tumor not visualized on US/CEUS.
Articolo in rivista - Articolo scientifico
CT renal arteriography; imaging guidance; kidney tumor; renal cell carcinoma; thermal ablation;
English
13-ago-2023
2023
40
1
2244706
none
Muglia, R., Marra, P., Dulcetta, L., Carbone, F., Sironi, S. (2023). CT renal arteriography as a novel imaging guidance for the percutaneous ablation of small renal tumors. INTERNATIONAL JOURNAL OF HYPERTHERMIA, 40(1) [10.1080/02656736.2023.2244706].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/470663
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