Purpose: Hoya one-day multifocal (HOM) is a new contact lens for presbyopia with the following characteristics: silicone hydrogel, 48% water content, Dk140, UVA/B-blocking, handling tint, centrenear multifocal design. The purpose is to compare this in a non-inferiority crossover trial with Alcon Dailies Total 1 multifocal (DTM). Method: Sixty participants (20 in London, 20 in Milan, 20 in Aarhus) underwent baseline testing and then wore each lens type for 2 weeks. Preliminary analyses are presented of key outcome variables (lens preference, VF-14 questionnaire, binocular visual acuity [VA] at distance and near, stereoacuity, speed of reading with Wilkins Rate of Reading Test [WRRT]) and measurements relevant to dry eye. Results: At the end of the trial, 23 participants preferred HOM and 31 DTM, with 6 unable to choose. Of those who expressed a preference, the proportion preferring each type did not differ significantly from chance (sign test, p=0.34). At the end of each wearing period, the proportion who were prepared to buy each type was similar (HOM, 27/60; DTM 30/60), as were gradings of the ease of handling with each lens type (p=0.28). DTM gave slightly better (less than one line difference) median distance VA (p=0.004). There were no significant differences between the lens types in near VA (p>0.2), near stereoacuity (p=0.18), WRRT (p=0.26), and VF-14 visual symptom questionnaire (p=0.53). Participants with higher (worse) baseline scores for lid redness and corneal staining were more likely to prefer DTM (p<0.03). Conversely, participants with scores more suggestive of dry eye (higher OSDI and Pult Meibography scores and lower FBUT) were more likely to prefer HOM (p<0.004). Participants with larger photopic pupil sizes were more likely to prefer HOM (p=0.009). Conclusions: These preliminary results indicate that lens preference is influenced by patient parameters. Further analyses of extensive data from daily diaries are underway.
Zeri, F., Lauenborg, B., Yammouni, R., Evans, B., Tavazzi, S., Rizzo, G., et al. (2024). Crossover trial of a new one-day disposable multifocal contact lens: preliminary report. Intervento presentato a: NCC2024. FUTURE GENERATION 2024, Veldhoven the Netherlands..
Crossover trial of a new one-day disposable multifocal contact lens: preliminary report
Fabrizio Zeri;Silvia Tavazzi;Giulia Carlotta Rizzo;
2024
Abstract
Purpose: Hoya one-day multifocal (HOM) is a new contact lens for presbyopia with the following characteristics: silicone hydrogel, 48% water content, Dk140, UVA/B-blocking, handling tint, centrenear multifocal design. The purpose is to compare this in a non-inferiority crossover trial with Alcon Dailies Total 1 multifocal (DTM). Method: Sixty participants (20 in London, 20 in Milan, 20 in Aarhus) underwent baseline testing and then wore each lens type for 2 weeks. Preliminary analyses are presented of key outcome variables (lens preference, VF-14 questionnaire, binocular visual acuity [VA] at distance and near, stereoacuity, speed of reading with Wilkins Rate of Reading Test [WRRT]) and measurements relevant to dry eye. Results: At the end of the trial, 23 participants preferred HOM and 31 DTM, with 6 unable to choose. Of those who expressed a preference, the proportion preferring each type did not differ significantly from chance (sign test, p=0.34). At the end of each wearing period, the proportion who were prepared to buy each type was similar (HOM, 27/60; DTM 30/60), as were gradings of the ease of handling with each lens type (p=0.28). DTM gave slightly better (less than one line difference) median distance VA (p=0.004). There were no significant differences between the lens types in near VA (p>0.2), near stereoacuity (p=0.18), WRRT (p=0.26), and VF-14 visual symptom questionnaire (p=0.53). Participants with higher (worse) baseline scores for lid redness and corneal staining were more likely to prefer DTM (p<0.03). Conversely, participants with scores more suggestive of dry eye (higher OSDI and Pult Meibography scores and lower FBUT) were more likely to prefer HOM (p<0.004). Participants with larger photopic pupil sizes were more likely to prefer HOM (p=0.009). Conclusions: These preliminary results indicate that lens preference is influenced by patient parameters. Further analyses of extensive data from daily diaries are underway.
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