Moloney murine leukemia virus (MMLV)-based vectors have been widely used in vitro and in clinical studies. Subsequently, HIV-1 derived lentivectors were introduced1 in which the env, vif, vpr, vpu and nef genes are deleted.2 Another version of the lentivector has been developed which contains a 118 bp non-coding sequence from the HIV-1 pol gene.3,4 We compare the capacity of these different retroviruses5-7 to transduce human hematopoietic lines.

Bambacioni, F., Casati, C., Serafini, M., Manganini, M., Golay, J., Introna, M. (2001). Lentiviral vectors show dramatically increased efficiency of transduction of human leukemic cell lines. HAEMATOLOGICA, 86(10), 1095-1096.

Lentiviral vectors show dramatically increased efficiency of transduction of human leukemic cell lines

Serafini M;
2001

Abstract

Moloney murine leukemia virus (MMLV)-based vectors have been widely used in vitro and in clinical studies. Subsequently, HIV-1 derived lentivectors were introduced1 in which the env, vif, vpr, vpu and nef genes are deleted.2 Another version of the lentivector has been developed which contains a 118 bp non-coding sequence from the HIV-1 pol gene.3,4 We compare the capacity of these different retroviruses5-7 to transduce human hematopoietic lines.
Articolo in rivista - Articolo scientifico
Gene transfer; Lentivirol vectors; Leukemia cell lines;
English
2001
86
10
1095
1096
none
Bambacioni, F., Casati, C., Serafini, M., Manganini, M., Golay, J., Introna, M. (2001). Lentiviral vectors show dramatically increased efficiency of transduction of human leukemic cell lines. HAEMATOLOGICA, 86(10), 1095-1096.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/459439
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