The discovery of heme-induced respiration in Lactococcus lactis has radically improved the industrial processes used for the biomass production of this species. Here, we show that inhibition of the lactate dehydrogenase activity of L. lactis during growth under respiration-permissive conditions can stimulate aerobic respiration, thereby increasing not only growth efficiency but also the robustness of this organism.
Arioli, S., Zambelli, D., Guglielmetti, S., De Noni, I., Pedersen, M., Pedersen, P., et al. (2013). Increasing the heme-dependent respiratory efficiency in Lactococcus lactis by inhibition of lactate dehydrogenase. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 79(1), 376-380 [10.1128/AEM.02734-12].
Increasing the heme-dependent respiratory efficiency in Lactococcus lactis by inhibition of lactate dehydrogenase
Guglielmetti, S;
2013
Abstract
The discovery of heme-induced respiration in Lactococcus lactis has radically improved the industrial processes used for the biomass production of this species. Here, we show that inhibition of the lactate dehydrogenase activity of L. lactis during growth under respiration-permissive conditions can stimulate aerobic respiration, thereby increasing not only growth efficiency but also the robustness of this organism.
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