The organization of the descending projections from the intralaminar parafascicular nucleus was studied using biocytin as an anterograde tracer in rats. After biocytin injection into the lateral parafascicular nucleus, three bundles of fibers descending throughout the brainstem were seen. Terminal fields were found in several structures, for example the lateral geniculate nucleus, nucleus reticularis thalami, subthalamus, zona incerta, substantia nigra, red nucleus, periaqueductal gray, superior colliculus, reticular formation, raphe nuclei, pontine nuclei, trigeminal complex, and ventral horn of the spinal cord. Different types of labeled terminals (small terminal boutons, en passant varicosities, large claw-like terminals) were observed, particularly in the substantia nigra and reticular formation where the density of terminals was highest. The organization of these extensive descending connections to both motor and sensory structures does not allow functions to be conclusively attributed to the parafascicular nucleus neurons. Further investigations are required to resolve this question

Marini, G., Pianca, L., Tredici, G. (1999). Descending projections arising from the parafascicular nucleus in rats: trajectory of fibers, projection pattern and mapping of terminations. SOMATOSENSORY & MOTOR RESEARCH, 16(3), 207-222 [10.1080/08990229970465].

Descending projections arising from the parafascicular nucleus in rats: trajectory of fibers, projection pattern and mapping of terminations

Tredici, G
1999

Abstract

The organization of the descending projections from the intralaminar parafascicular nucleus was studied using biocytin as an anterograde tracer in rats. After biocytin injection into the lateral parafascicular nucleus, three bundles of fibers descending throughout the brainstem were seen. Terminal fields were found in several structures, for example the lateral geniculate nucleus, nucleus reticularis thalami, subthalamus, zona incerta, substantia nigra, red nucleus, periaqueductal gray, superior colliculus, reticular formation, raphe nuclei, pontine nuclei, trigeminal complex, and ventral horn of the spinal cord. Different types of labeled terminals (small terminal boutons, en passant varicosities, large claw-like terminals) were observed, particularly in the substantia nigra and reticular formation where the density of terminals was highest. The organization of these extensive descending connections to both motor and sensory structures does not allow functions to be conclusively attributed to the parafascicular nucleus neurons. Further investigations are required to resolve this question
Articolo in rivista - Articolo scientifico
Animals; Age Factors; Spinal Cord; Lysine; Microinjections; Red Nucleus; Raphe Nuclei; Anterior Horn Cells; Geniculate Bodies; Rats; Brain Mapping; Intralaminar Thalamic Nuclei; Efferent Pathways; Trigeminal Nuclei; Superior Colliculi; Rats, Wistar; Brain Stem; Substantia Nigra; Subthalamus; Reticular Formation; Pons
English
1999
16
3
207
222
none
Marini, G., Pianca, L., Tredici, G. (1999). Descending projections arising from the parafascicular nucleus in rats: trajectory of fibers, projection pattern and mapping of terminations. SOMATOSENSORY & MOTOR RESEARCH, 16(3), 207-222 [10.1080/08990229970465].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/45720
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