Neurologic prognosis of comatose patients with epileptiform EEG activity after cardiac arrest is an important and unsettled issue.(1) Although clinical seizures and epileptiform EEG are negative prognostic indicators,(2) recent studies indicate that some of these patients achieve a good neurologic outcome with a timely diagnosis and appropriate treatment with a combination of antiepileptic drugs and anesthetics.(3,4) In this setting, the balance between treatment futility and premature withdrawal of care is delicate, and the risk of making unjustified decisions is real.(5,6) Therefore, a reliable prognostic score for postanoxic patients with epileptiform EEG would greatly benefit physicians, families, and patients.
Beretta, S., Coppo, A. (2020). Post-cardiac arrest patients with epileptiform EEG: Better selection for better treatment. NEUROLOGY, 94(16), 685-686 [10.1212/WNL.0000000000009282].
Post-cardiac arrest patients with epileptiform EEG: Better selection for better treatment
Beretta S.
;
2020
Abstract
Neurologic prognosis of comatose patients with epileptiform EEG activity after cardiac arrest is an important and unsettled issue.(1) Although clinical seizures and epileptiform EEG are negative prognostic indicators,(2) recent studies indicate that some of these patients achieve a good neurologic outcome with a timely diagnosis and appropriate treatment with a combination of antiepileptic drugs and anesthetics.(3,4) In this setting, the balance between treatment futility and premature withdrawal of care is delicate, and the risk of making unjustified decisions is real.(5,6) Therefore, a reliable prognostic score for postanoxic patients with epileptiform EEG would greatly benefit physicians, families, and patients.
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