Increasing evidence links intestinal permeability (IP), a feature of the intestinal barrier, to several pathological or dysfunctional conditions. Several host and environmental factors, including dietary factors, can affect the maintenance of normal IP. In this regard, food bioactives, such as polyphenols, have been proposed as potential IP modulators, even if the mechanisms involved are not yet fully elucidated. The aim of the present paper is to provide a short overview of the main evidence from in vitro and in vivo studies supporting the role of polyphenols in modulating IP and briefly discuss future perspectives in this research area.
Bernardi, S., Del Bo’, C., Marino, M., Gargari, G., Cherubini, A., Andres-Lacueva, C., et al. (2020). Polyphenols and Intestinal Permeability: Rationale and Future Perspectives. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 68(7), 1816-1829 [10.1021/acs.jafc.9b02283].
Polyphenols and Intestinal Permeability: Rationale and Future Perspectives
Simone GuglielmettiPenultimo
;
2020
Abstract
Increasing evidence links intestinal permeability (IP), a feature of the intestinal barrier, to several pathological or dysfunctional conditions. Several host and environmental factors, including dietary factors, can affect the maintenance of normal IP. In this regard, food bioactives, such as polyphenols, have been proposed as potential IP modulators, even if the mechanisms involved are not yet fully elucidated. The aim of the present paper is to provide a short overview of the main evidence from in vitro and in vivo studies supporting the role of polyphenols in modulating IP and briefly discuss future perspectives in this research area.File | Dimensione | Formato | |
---|---|---|---|
Bernardi-2020-J Agric Food Chem-VoR.pdf
accesso aperto
Tipologia di allegato:
Publisher’s Version (Version of Record, VoR)
Licenza:
Altro
Dimensione
713.72 kB
Formato
Adobe PDF
|
713.72 kB | Adobe PDF | Visualizza/Apri |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.