Increasing evidence links intestinal permeability (IP), a feature of the intestinal barrier, to several pathological or dysfunctional conditions. Several host and environmental factors, including dietary factors, can affect the maintenance of normal IP. In this regard, food bioactives, such as polyphenols, have been proposed as potential IP modulators, even if the mechanisms involved are not yet fully elucidated. The aim of the present paper is to provide a short overview of the main evidence from in vitro and in vivo studies supporting the role of polyphenols in modulating IP and briefly discuss future perspectives in this research area.

Bernardi, S., Del Bo’, C., Marino, M., Gargari, G., Cherubini, A., Andres-Lacueva, C., et al. (2020). Polyphenols and Intestinal Permeability: Rationale and Future Perspectives. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 68(7), 1816-1829 [10.1021/acs.jafc.9b02283].

Polyphenols and Intestinal Permeability: Rationale and Future Perspectives

Simone Guglielmetti
Penultimo
;
2020

Abstract

Increasing evidence links intestinal permeability (IP), a feature of the intestinal barrier, to several pathological or dysfunctional conditions. Several host and environmental factors, including dietary factors, can affect the maintenance of normal IP. In this regard, food bioactives, such as polyphenols, have been proposed as potential IP modulators, even if the mechanisms involved are not yet fully elucidated. The aim of the present paper is to provide a short overview of the main evidence from in vitro and in vivo studies supporting the role of polyphenols in modulating IP and briefly discuss future perspectives in this research area.
Articolo in rivista - Articolo scientifico
animal studies; human studies; in vitro studies; intestinal permeability; polyphenols;
English
24-giu-2019
2020
68
7
1816
1829
open
Bernardi, S., Del Bo’, C., Marino, M., Gargari, G., Cherubini, A., Andres-Lacueva, C., et al. (2020). Polyphenols and Intestinal Permeability: Rationale and Future Perspectives. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 68(7), 1816-1829 [10.1021/acs.jafc.9b02283].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/452838
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