A novel multicomponent vaccine against meningococcal capsular group B (MenB) disease contains four major components: factor-H-binding protein, neisserial heparin binding antigen, neisserial adhesin A, and outer-membrane vesicles derived from the strain NZ98/254. Because the public health effect of the vaccine, 4CMenB (Novartis Vaccines and Diagnostics, Siena, Italy), is unclear, we assessed the predicted strain coverage in Europe.

Vogel, U., Taha, M., Vazquez, J., Findlow, J., Claus, H., Stefanelli, P., et al. (2013). Predicted strain coverage of a meningococcal multicomponent vaccine (4CMenB) in Europe: a qualitative and quantitative assessment. THE LANCET INFECTIOUS DISEASES, 13(5), 416-425 [10.1016/S1473-3099(13)70006-9].

Predicted strain coverage of a meningococcal multicomponent vaccine (4CMenB) in Europe: a qualitative and quantitative assessment

LOVAGLIO, PIETRO GIORGIO;
2013

Abstract

A novel multicomponent vaccine against meningococcal capsular group B (MenB) disease contains four major components: factor-H-binding protein, neisserial heparin binding antigen, neisserial adhesin A, and outer-membrane vesicles derived from the strain NZ98/254. Because the public health effect of the vaccine, 4CMenB (Novartis Vaccines and Diagnostics, Siena, Italy), is unclear, we assessed the predicted strain coverage in Europe.
Articolo in rivista - Articolo scientifico
Meningococcal Vaccines; Genes, Bacterial; Adhesins, Bacterial; Reproducibility of Results; DNA, Bacterial; Humans; Meningitis, Meningococcal; Predictive Value of Tests; Europe; Bacterial Typing Techniques; Multilocus Sequence Typing; Population Surveillance; Genotype; Neisseria meningitidis, Serogroup B; Antigens, Bacterial; Enzyme-Linked Immunosorbent Assay; Geography
English
2013
13
5
416
425
none
Vogel, U., Taha, M., Vazquez, J., Findlow, J., Claus, H., Stefanelli, P., et al. (2013). Predicted strain coverage of a meningococcal multicomponent vaccine (4CMenB) in Europe: a qualitative and quantitative assessment. THE LANCET INFECTIOUS DISEASES, 13(5), 416-425 [10.1016/S1473-3099(13)70006-9].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/45225
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