Producers of probiotic products are legally required to indicate on the label only the minimum numbers of viable microorganisms at the end of shelf life expressed as colony-forming units (CFUs). Label specifications, however, describe only a fraction of the actual microbiological content of a probiotic formulation. This paper describes the microbiological components of a probiotic product that are not mentioned on the label, such as the actual number of CFUs, the presence of viable cells that cannot generate colonies on agar plates, and the abundance of dead cells. These “hidden” microbial fractions in probiotic products, the abundance of which may change during the shelf life, can promote biological responses in the host. Therefore, they should not be ignored because they may influence the efficacy and can be relevant for immunocompromised or fragile consumers. In conclusion, we propose the minimum requirements for microbiological characterization of probiotic products to be adopted for label specifications and clinical studies.

Fiore, W., Arioli, S., Guglielmetti, S. (2020). The neglected microbial components of commercial probiotic formulations. MICROORGANISMS, 8(8), 1-8 [10.3390/microorganisms8081177].

The neglected microbial components of commercial probiotic formulations

Guglielmetti, S
2020

Abstract

Producers of probiotic products are legally required to indicate on the label only the minimum numbers of viable microorganisms at the end of shelf life expressed as colony-forming units (CFUs). Label specifications, however, describe only a fraction of the actual microbiological content of a probiotic formulation. This paper describes the microbiological components of a probiotic product that are not mentioned on the label, such as the actual number of CFUs, the presence of viable cells that cannot generate colonies on agar plates, and the abundance of dead cells. These “hidden” microbial fractions in probiotic products, the abundance of which may change during the shelf life, can promote biological responses in the host. Therefore, they should not be ignored because they may influence the efficacy and can be relevant for immunocompromised or fragile consumers. In conclusion, we propose the minimum requirements for microbiological characterization of probiotic products to be adopted for label specifications and clinical studies.
Articolo in rivista - Articolo scientifico
Cell viability; Flow cytometry; Food supplements; Paraprobiotics; Postbiotics;
English
2020
8
8
1
8
1177
open
Fiore, W., Arioli, S., Guglielmetti, S. (2020). The neglected microbial components of commercial probiotic formulations. MICROORGANISMS, 8(8), 1-8 [10.3390/microorganisms8081177].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/451791
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