Prevention of infections is crucial in solid organ transplant (SOT) candidates and recipients. These patients are exposed to an increased infectious risk due to previous organ insufficiency and to pharmacologic immunosuppression. Besides infectious-related morbidity and mortality, this vulnerable group of patients is also exposed to the risk of acute decompensation and organ rejection or failure in the pre- and post-transplant period, respectively, since antimicrobial treatments are less effective than in the immunocompetent patients. Vaccination represents a major preventive measure against specific infectious risks in this population but as responses to vaccines are reduced, especially in the early post-transplant period or after treatment for rejection, an optimal vaccination status should be obtained prior to transplantation whenever possible. This review reports the currently available data on the indications and protocols of vaccination in SOT adult candidates and recipients.

Vigano, M., Beretta, M., Lepore, M., Abete, R., Benatti, S., Grassini, M., et al. (2023). Vaccination Recommendations in Solid Organ Transplant Adult Candidates and Recipients. VACCINES, 11(10) [10.3390/vaccines11101611].

Vaccination Recommendations in Solid Organ Transplant Adult Candidates and Recipients

Chiodini G.;Iachini M.;Neri F.;Ruggenenti P.;Colledan M.;Fagiuoli S.
2023

Abstract

Prevention of infections is crucial in solid organ transplant (SOT) candidates and recipients. These patients are exposed to an increased infectious risk due to previous organ insufficiency and to pharmacologic immunosuppression. Besides infectious-related morbidity and mortality, this vulnerable group of patients is also exposed to the risk of acute decompensation and organ rejection or failure in the pre- and post-transplant period, respectively, since antimicrobial treatments are less effective than in the immunocompetent patients. Vaccination represents a major preventive measure against specific infectious risks in this population but as responses to vaccines are reduced, especially in the early post-transplant period or after treatment for rejection, an optimal vaccination status should be obtained prior to transplantation whenever possible. This review reports the currently available data on the indications and protocols of vaccination in SOT adult candidates and recipients.
Articolo in rivista - Articolo scientifico
chronic diseases; heart; infections; kidney; liver; lungs; prevention; solid organ transplantation; vaccination;
English
18-ott-2023
2023
11
10
1611
open
Vigano, M., Beretta, M., Lepore, M., Abete, R., Benatti, S., Grassini, M., et al. (2023). Vaccination Recommendations in Solid Organ Transplant Adult Candidates and Recipients. VACCINES, 11(10) [10.3390/vaccines11101611].
File in questo prodotto:
File Dimensione Formato  
10281-449196_VoR.pdf

accesso aperto

Tipologia di allegato: Publisher’s Version (Version of Record, VoR)
Licenza: Creative Commons
Dimensione 360.41 kB
Formato Adobe PDF
360.41 kB Adobe PDF Visualizza/Apri

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/449196
Citazioni
  • Scopus 4
  • ???jsp.display-item.citation.isi??? 5
Social impact