Different attempts have been made to minimize the neurotoxicity of cisplatin (DDP) and the use of "neuroprotective" drugs seems to be a promising strategy. In rats we compared the effects on the dorsal root ganglia neurons and peripheral nerves of the administration of DDP alone or in combination with glutathione (GSH), a putative "neuroprotective" drug
Cavaletti, G., Minoia, C., Schieppati, M., Tredici, G. (1994). Protective effects of glutathione on cisplatin neurotoxicity in rats. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 29(4), 771-776 [10.1016/0360-3016(94)90565-7].
Protective effects of glutathione on cisplatin neurotoxicity in rats
CAVALETTI, GUIDO ANGELO;TREDICI, GIOVANNI
1994
Abstract
Different attempts have been made to minimize the neurotoxicity of cisplatin (DDP) and the use of "neuroprotective" drugs seems to be a promising strategy. In rats we compared the effects on the dorsal root ganglia neurons and peripheral nerves of the administration of DDP alone or in combination with glutathione (GSH), a putative "neuroprotective" drug
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