It is known that early sensory deprivation modifies brain functional structure and connectivity. The aim of the present study was to investigate the neuro-functional organization of reading in a patient with profound congenital unilateral deafness. Using event-related potentials (ERPs), we compared cortical networks supporting the processing of written words in patient RA (completely deaf in the right ear since birth) and in a group of control volunteers. We found that congenital unilateral hearing deprivation modifies neural mechanisms of word reading. Indeed, while written word processing was left-lateralized in controls, we found a strong right lateralization of the fusiform and inferior occipital gyri activation in RA. This finding goes in the same direction of recent proposals that the ventral occipito-temporal activity in word reading seem to lateralize to the same hemisphere as the one involved in spoken language processing

Adorni, R., Manfredi, M., Proverbio, A. (2013). Congenital Unilateral Deafness Affects Cerebral Organization of Reading. BRAIN SCIENCES, 3(2), 908-922 [10.3390/brainsci3020908].

Congenital Unilateral Deafness Affects Cerebral Organization of Reading

ADORNI, ROBERTA
;
MANFREDI, MIRELLA;PROVERBIO, ALICE MADO
2013

Abstract

It is known that early sensory deprivation modifies brain functional structure and connectivity. The aim of the present study was to investigate the neuro-functional organization of reading in a patient with profound congenital unilateral deafness. Using event-related potentials (ERPs), we compared cortical networks supporting the processing of written words in patient RA (completely deaf in the right ear since birth) and in a group of control volunteers. We found that congenital unilateral hearing deprivation modifies neural mechanisms of word reading. Indeed, while written word processing was left-lateralized in controls, we found a strong right lateralization of the fusiform and inferior occipital gyri activation in RA. This finding goes in the same direction of recent proposals that the ventral occipito-temporal activity in word reading seem to lateralize to the same hemisphere as the one involved in spoken language processing
Articolo in rivista - Articolo scientifico
ERPs; LORETA (low resolution electromagnetic tomography); N170; ventral occipito-temporal (vOT) cortex; reading; deafness; hemispheric asymmetry; neuroplasticity
English
2013
3
2
908
922
none
Adorni, R., Manfredi, M., Proverbio, A. (2013). Congenital Unilateral Deafness Affects Cerebral Organization of Reading. BRAIN SCIENCES, 3(2), 908-922 [10.3390/brainsci3020908].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/44460
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