Non-invasive assessment of fibrosis is a key step in prognostication and monitoring of patients with autoimmune liver diseases (AILDs). Vibration-controlled transient elastography (VCTE) has been the most widely used tool of fibrosis staging which showed high accuracy in identifying advanced fibrosis and cirrhosis in AILD. However, evidence about its accuracy are often based on retrospective cohort studies with small samples. Furthermore, the role of potential confounding factors (i.e. liver inflammation and cholestasis) has not been fully established yet. In this chapter, we review the evidence on the use of VCTE in AILDs focusing on strengths and limitations.
Cristoferi, L., Carbone, M., Invernizzi, P. (2021). Elastography in Autoimmune Liver Diseases. In M. Fraquelli (a cura di), Elastography of the Liver and Beyond (pp. 91-103). Springer International Publishing [10.1007/978-3-030-74132-7_7].
Elastography in Autoimmune Liver Diseases
Cristoferi L.
;Carbone M.;Invernizzi P.
2021
Abstract
Non-invasive assessment of fibrosis is a key step in prognostication and monitoring of patients with autoimmune liver diseases (AILDs). Vibration-controlled transient elastography (VCTE) has been the most widely used tool of fibrosis staging which showed high accuracy in identifying advanced fibrosis and cirrhosis in AILD. However, evidence about its accuracy are often based on retrospective cohort studies with small samples. Furthermore, the role of potential confounding factors (i.e. liver inflammation and cholestasis) has not been fully established yet. In this chapter, we review the evidence on the use of VCTE in AILDs focusing on strengths and limitations.
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