In this issue of Blood, Ludwig et al characterize a rare form of inherited hemolytic anemia. They identified novel mutations in an intrinsically disordered region (IDR) in the GATA1 carboxyl (C)-terminal domain, which underlie novel functions in selectively regulating GATA1 chromatin occupancies in erythropoiesis.(1)
Strouboulis, J., Ronchi, A. (2022). GATA1: function through disorder. BLOOD, 139(16), 2422-2423 [10.1182/blood.2021015351].
GATA1: function through disorder
Ronchi A. E.
2022
Abstract
In this issue of Blood, Ludwig et al characterize a rare form of inherited hemolytic anemia. They identified novel mutations in an intrinsically disordered region (IDR) in the GATA1 carboxyl (C)-terminal domain, which underlie novel functions in selectively regulating GATA1 chromatin occupancies in erythropoiesis.(1)
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