This pilot study assessed neuro-cognitive functioning in 7 adults treated with Vagus Nerve Stimulation (VNS) for refractory epilepsy over a 12-month period. All patients were assessed using the Critical Flicker Fusion (CFF) test, a sensitive measure of the ability of the central nervous system to discriminate items of sensory information, along with a standardized battery of neuropsychological and behavioral measures. Reduction in seizure frequency and psychiatric ratings was accompanied by a selective but significant (p <.05) improvement in CFF performance. These findings suggest that the CFF test could be a useful indicator of improvement in neurocognitive functioning during VNS.
Achinivu, K., Staufenberg, E., Cull, C., Cavanna, A., Ring, H. (2012). Cognitive Function during Vagus Nerve Stimulation (VNS) for treatment-refractory epilepsy: a Pilot Study using the Critical Flicker Fusion (CFF) Test. JOURNAL OF NEUROTHERAPY, 16(1), 32-36 [10.1080/10874208.2012.650097].
Cognitive Function during Vagus Nerve Stimulation (VNS) for treatment-refractory epilepsy: a Pilot Study using the Critical Flicker Fusion (CFF) Test
Cavanna A
;
2012
Abstract
This pilot study assessed neuro-cognitive functioning in 7 adults treated with Vagus Nerve Stimulation (VNS) for refractory epilepsy over a 12-month period. All patients were assessed using the Critical Flicker Fusion (CFF) test, a sensitive measure of the ability of the central nervous system to discriminate items of sensory information, along with a standardized battery of neuropsychological and behavioral measures. Reduction in seizure frequency and psychiatric ratings was accompanied by a selective but significant (p <.05) improvement in CFF performance. These findings suggest that the CFF test could be a useful indicator of improvement in neurocognitive functioning during VNS.File | Dimensione | Formato | |
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