Gastric cancer (GC) is a relevant public health issue as its incidence and mortality rates are growing worldwide. There are recognized carcinogen agents, such as obesity, tobacco, meat, alcohol consumption and some dietary protective factors. Strategies of early diagnosis through population-based surveillance programs have been demonstrated to be effective in lowering the morbidity and mortality related to GC in some countries. Indeed, the detection of early lesions is very important in order to offer minimally invasive treatments. Endoscopic resection is the gold standard for lesions with a low risk of lymph node metastasis, whereas surgical mini-invasive approaches can be considered in early lesions when endoscopy is not curative. This review outlines the role of lifestyle and prevention strategies for GC, in order to reduce the patients’ risk factors, implement the surveillance of precancerous conditions and, therefore, improve the diagnosis of early lesions. Furthermore, we summarize the available treatments for early gastric cancer.

Conti, C., Agnesi, S., Scaravaglio, M., Masseria, P., Dinelli, M., Oldani, M., et al. (2023). Early Gastric Cancer: Update on Prevention, Diagnosis and Treatment. INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 20(3) [10.3390/ijerph20032149].

Early Gastric Cancer: Update on Prevention, Diagnosis and Treatment

Agnesi, Stefano;Scaravaglio, Miki;Masseria, Pietro;Oldani, Massimo;Uggeri, Fabio
2023

Abstract

Gastric cancer (GC) is a relevant public health issue as its incidence and mortality rates are growing worldwide. There are recognized carcinogen agents, such as obesity, tobacco, meat, alcohol consumption and some dietary protective factors. Strategies of early diagnosis through population-based surveillance programs have been demonstrated to be effective in lowering the morbidity and mortality related to GC in some countries. Indeed, the detection of early lesions is very important in order to offer minimally invasive treatments. Endoscopic resection is the gold standard for lesions with a low risk of lymph node metastasis, whereas surgical mini-invasive approaches can be considered in early lesions when endoscopy is not curative. This review outlines the role of lifestyle and prevention strategies for GC, in order to reduce the patients’ risk factors, implement the surveillance of precancerous conditions and, therefore, improve the diagnosis of early lesions. Furthermore, we summarize the available treatments for early gastric cancer.
Articolo in rivista - Articolo scientifico
early gastric cancer; endoscopic submucosal dissection; gastric cancer; Helicobacter pylori; upper endoscopy;
English
25-gen-2023
2023
20
3
2149
open
Conti, C., Agnesi, S., Scaravaglio, M., Masseria, P., Dinelli, M., Oldani, M., et al. (2023). Early Gastric Cancer: Update on Prevention, Diagnosis and Treatment. INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 20(3) [10.3390/ijerph20032149].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/407457
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