Inhibitory control is the capacity to withhold or suppress a thought or action intentionally. The anterior Midcingulate Cortex (aMCC) participates in response inhibition, a proxy measure of inhibitory control. Recent research suggests that response inhibition is modulated by individual variability in the aMCC sulcal morphology. However, no study has investigated if this phenomenon is associated with neurofunctional differences during a task. In this study, 42 participants performed an Attention Network Task and a Numerical Stroop task in an MRI scanner. We investigated differences in brain activity and response inhibition efficiency between individuals with symmetric and asymmetric aMCC sulcal patterns. The results showed that aMCC morphological variability is partly associated with inhibitory control, and revealed greater activation in individuals with symmetric patterns during the Stroop task. Our findings provide novel insights into the functional correlates of the relationship between aMCC morphology and executive abilities.

Fedeli, D., Del Maschio, N., Del Mauro, G., Defendenti, F., Sulpizio, S., Abutalebi, J. (2022). Cingulate cortex morphology impacts on neurofunctional activity and behavioral performance in interference tasks. SCIENTIFIC REPORTS, 12(1) [10.1038/s41598-022-17557-6].

Cingulate cortex morphology impacts on neurofunctional activity and behavioral performance in interference tasks

Sulpizio S.;
2022

Abstract

Inhibitory control is the capacity to withhold or suppress a thought or action intentionally. The anterior Midcingulate Cortex (aMCC) participates in response inhibition, a proxy measure of inhibitory control. Recent research suggests that response inhibition is modulated by individual variability in the aMCC sulcal morphology. However, no study has investigated if this phenomenon is associated with neurofunctional differences during a task. In this study, 42 participants performed an Attention Network Task and a Numerical Stroop task in an MRI scanner. We investigated differences in brain activity and response inhibition efficiency between individuals with symmetric and asymmetric aMCC sulcal patterns. The results showed that aMCC morphological variability is partly associated with inhibitory control, and revealed greater activation in individuals with symmetric patterns during the Stroop task. Our findings provide novel insights into the functional correlates of the relationship between aMCC morphology and executive abilities.
Articolo in rivista - Articolo scientifico
Brain Mapping; Humans; Magnetic Resonance Imaging; Gyrus Cinguli; Nervous System Physiological Phenomena
English
11-ago-2022
2022
12
1
13684
open
Fedeli, D., Del Maschio, N., Del Mauro, G., Defendenti, F., Sulpizio, S., Abutalebi, J. (2022). Cingulate cortex morphology impacts on neurofunctional activity and behavioral performance in interference tasks. SCIENTIFIC REPORTS, 12(1) [10.1038/s41598-022-17557-6].
File in questo prodotto:
File Dimensione Formato  
Fedeli-2022-Scient Rep-VoR.pdf

accesso aperto

Descrizione: Article
Tipologia di allegato: Publisher’s Version (Version of Record, VoR)
Licenza: Creative Commons
Dimensione 1.53 MB
Formato Adobe PDF
1.53 MB Adobe PDF Visualizza/Apri

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/403978
Citazioni
  • Scopus 3
  • ???jsp.display-item.citation.isi??? 2
Social impact