The peculiarity of glycans expressed in humans, in both physiologic and pathologic state, and in pathogenic organisms, is unveiling precious information useful for the early detection of cancers, acute and chronic inflammatory states and infections. Indeed, the glycocode dynamism and the wide range of functions covered by glycans are pivotal in the development of the most recent pioneering and effective nanoprobes eligible as ultrasensitive biosensors for multiple diseases, strongly impacting on clinical diagnostic strategies. In this report, the current, forthcoming and potential diagnostic use of glycans, in combination with advanced nanomaterials, is discussed.

Barbugian, F., Cadamuro, F., Magli, S., Nicotra, F., Rossi, L., Russo, L. (2021). Diagnostic glycotools. In A. Rauter, T. Lindhorst, Y. Queneau (a cura di), Carbohydrate Chemistry. Chemical and Biological Approaches, Volume 45 (pp. 572-608). Royal Society of Chemistry [10.1039/9781839164538-00572].

Diagnostic glycotools

Barbugian, F;Cadamuro, F;Magli, S;Nicotra, F
;
Rossi, L;Russo, L
2021

Abstract

The peculiarity of glycans expressed in humans, in both physiologic and pathologic state, and in pathogenic organisms, is unveiling precious information useful for the early detection of cancers, acute and chronic inflammatory states and infections. Indeed, the glycocode dynamism and the wide range of functions covered by glycans are pivotal in the development of the most recent pioneering and effective nanoprobes eligible as ultrasensitive biosensors for multiple diseases, strongly impacting on clinical diagnostic strategies. In this report, the current, forthcoming and potential diagnostic use of glycans, in combination with advanced nanomaterials, is discussed.
Capitolo o saggio
Diagnosis; Chronic inflammatory; Clinical diagnostics; Diagnostic strategy; Glycans; Pathogenic organisms; Ultrasensitive; Polysaccharides
English
Carbohydrate Chemistry. Chemical and Biological Approaches, Volume 45
2021
978-1-83916-390-6
PDF ISBN: 978-1-83916-453-8; EPUB ISBN: 978-1-83916-454-5
Barbugian, F., Cadamuro, F., Magli, S., Nicotra, F., Rossi, L., Russo, L. (2021). Diagnostic glycotools. In A. Rauter, T. Lindhorst, Y. Queneau (a cura di), Carbohydrate Chemistry. Chemical and Biological Approaches, Volume 45 (pp. 572-608). Royal Society of Chemistry [10.1039/9781839164538-00572].
Barbugian, F; Cadamuro, F; Magli, S; Nicotra, F; Rossi, L; Russo, L
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/402798
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