Introduction: Converging evidence from both clinical and experimental studies has shown that Tourette syndrome (TS) is not a unitary condition, but a cluster of multiple phenotypes, which encompass both tics and specific behavioural and cognitive symptoms (mainly attention-deficit and hyperactivity disorder and obsessive-compulsive disorder). Methods: We conducted a narrative review of the recent literature on the cognitive neuropsychiatry of TS. Results: Although clinical research has shown that TS is not associated with cognitive deficits per se, the findings of recent studies have suggested the presence of subtle alterations in specific cognitive functions. A promising line of research on imitative behaviour could provide a common background for the alterations in executive control and social cognition observed in TS. Two different (but not mutually exclusive) neurocognitive theories have recently suggested that TS could originate from altered perception-action binding and social decision-making dysfunction, respectively. Conclusions: Since the presence of behavioural comorbidities influences individualised treatment approaches, it is likely that a more precise characterisation of TS phenotypes, including cognitive aspects, will result in improved levels of care for patients with tic disorders.

Cavanna, A., Ganos, C., Hartmann, A., Martino, D., Pringsheim, T., Seri, S. (2020). The cognitive neuropsychiatry of Tourette syndrome. COGNITIVE NEUROPSYCHIATRY, 25(4), 254-268 [10.1080/13546805.2020.1760812].

The cognitive neuropsychiatry of Tourette syndrome

Cavanna A
;
2020

Abstract

Introduction: Converging evidence from both clinical and experimental studies has shown that Tourette syndrome (TS) is not a unitary condition, but a cluster of multiple phenotypes, which encompass both tics and specific behavioural and cognitive symptoms (mainly attention-deficit and hyperactivity disorder and obsessive-compulsive disorder). Methods: We conducted a narrative review of the recent literature on the cognitive neuropsychiatry of TS. Results: Although clinical research has shown that TS is not associated with cognitive deficits per se, the findings of recent studies have suggested the presence of subtle alterations in specific cognitive functions. A promising line of research on imitative behaviour could provide a common background for the alterations in executive control and social cognition observed in TS. Two different (but not mutually exclusive) neurocognitive theories have recently suggested that TS could originate from altered perception-action binding and social decision-making dysfunction, respectively. Conclusions: Since the presence of behavioural comorbidities influences individualised treatment approaches, it is likely that a more precise characterisation of TS phenotypes, including cognitive aspects, will result in improved levels of care for patients with tic disorders.
Articolo in rivista - Articolo scientifico
attention-deficit and hyperactivity disorder; behaviour; cognitive neuropsychiatry; health-related quality of life; obsessive-compulsive disorder; perception-action binding; premonitory urges; social decision-making; tics; Tourette syndrome;
English
2020
25
4
254
268
reserved
Cavanna, A., Ganos, C., Hartmann, A., Martino, D., Pringsheim, T., Seri, S. (2020). The cognitive neuropsychiatry of Tourette syndrome. COGNITIVE NEUROPSYCHIATRY, 25(4), 254-268 [10.1080/13546805.2020.1760812].
File in questo prodotto:
File Dimensione Formato  
Cavanna-2020-Cognitive Neuropsychiatry-VoR.pdf

Solo gestori archivio

Descrizione: Article
Tipologia di allegato: Publisher’s Version (Version of Record, VoR)
Licenza: Tutti i diritti riservati
Dimensione 1.29 MB
Formato Adobe PDF
1.29 MB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/401780
Citazioni
  • Scopus 9
  • ???jsp.display-item.citation.isi??? 9
Social impact