Gilles de la Tourette syndrome is a chronic and complex tic disorder accompanied by specific behavioral problems in the majority of patients. With its multifaceted interplay between motion and emotion, this condition is a paradigmatic example of the science and art of clinical neuropsychiatry. This review article encompasses the clinical phenomenology of motor and vocal tics and associated sensory experiences (premonitory urges), as well as the behavioral spectrum of the most common comorbidities, including obsessive-compulsive disorder, attention-deficit and hyperactivity disorder, affective symptoms, and impulsivity. Knowledge of the contributions of both tics and behavioral problems to patients' health-related quality of life across the lifespan should assist treating clinicians in formulating a targeted management plan. Although the exact pathophysiology of Gilles de la Tourette syndrome remains elusive, research into therapeutic interventions has expanded the range of available interventions across multiple domains. A thorough understanding of the neurology and psychiatry of this condition is of key importance to meet the needs of this patient population, from the formulation of an accurate diagnosis to the implementation of effective treatment strategies.

Cavanna, A. (2018). Gilles de la Tourette syndrome as a paradigmatic neuropsychiatric disorder. CNS SPECTRUMS, 23(3), 213-218 [10.1017/S1092852918000834].

Gilles de la Tourette syndrome as a paradigmatic neuropsychiatric disorder

Cavanna A
2018

Abstract

Gilles de la Tourette syndrome is a chronic and complex tic disorder accompanied by specific behavioral problems in the majority of patients. With its multifaceted interplay between motion and emotion, this condition is a paradigmatic example of the science and art of clinical neuropsychiatry. This review article encompasses the clinical phenomenology of motor and vocal tics and associated sensory experiences (premonitory urges), as well as the behavioral spectrum of the most common comorbidities, including obsessive-compulsive disorder, attention-deficit and hyperactivity disorder, affective symptoms, and impulsivity. Knowledge of the contributions of both tics and behavioral problems to patients' health-related quality of life across the lifespan should assist treating clinicians in formulating a targeted management plan. Although the exact pathophysiology of Gilles de la Tourette syndrome remains elusive, research into therapeutic interventions has expanded the range of available interventions across multiple domains. A thorough understanding of the neurology and psychiatry of this condition is of key importance to meet the needs of this patient population, from the formulation of an accurate diagnosis to the implementation of effective treatment strategies.
Articolo in rivista - Articolo scientifico
Attention-deficit and hyperactivity disorder; behavior; Gilles de la Tourette syndrome; health-related quality of life; obsessive-compulsive disorder; premonitory urges; tics;
English
2018
23
3
213
218
reserved
Cavanna, A. (2018). Gilles de la Tourette syndrome as a paradigmatic neuropsychiatric disorder. CNS SPECTRUMS, 23(3), 213-218 [10.1017/S1092852918000834].
File in questo prodotto:
File Dimensione Formato  
Cavanna-2018-CNS Spectrum-VoR.pdf

Solo gestori archivio

Descrizione: Review
Tipologia di allegato: Publisher’s Version (Version of Record, VoR)
Licenza: Tutti i diritti riservati
Dimensione 205.28 kB
Formato Adobe PDF
205.28 kB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/401635
Citazioni
  • Scopus 37
  • ???jsp.display-item.citation.isi??? 34
Social impact