Motor and vocal tics are relatively common motor manifestations identified as the core features of Tourette’s syndrome (TS). Although traditional descriptions have focused on objective phenomenological observations, such as anatomical location, number and frequency of tics, patients’ first-person accounts have consistently reported characteristic subjective correlates. These sensory phenomena are often described as a feeling of mounting inner tension or urge to move (“premonitory urge”), which is transiently relieved by tic expression. This article reviews the existing literature on the clinical and neurobiological aspects of the premonitory urge in patients with TS, with focus on its pathophysiology and possible treatment implications.

Cavanna, A., Black, K., Hallett, M., Voon, V. (2017). Neurobiology of the premonitory urge in Tourette syndrome: Pathophysiology and treatment implications. THE JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES, 29(2), 95-104 [10.1176/appi.neuropsych.16070141].

Neurobiology of the premonitory urge in Tourette syndrome: Pathophysiology and treatment implications

Cavanna A
;
2017

Abstract

Motor and vocal tics are relatively common motor manifestations identified as the core features of Tourette’s syndrome (TS). Although traditional descriptions have focused on objective phenomenological observations, such as anatomical location, number and frequency of tics, patients’ first-person accounts have consistently reported characteristic subjective correlates. These sensory phenomena are often described as a feeling of mounting inner tension or urge to move (“premonitory urge”), which is transiently relieved by tic expression. This article reviews the existing literature on the clinical and neurobiological aspects of the premonitory urge in patients with TS, with focus on its pathophysiology and possible treatment implications.
Articolo in rivista - Articolo scientifico
Basal Ganglia Disorders; Brain Development and Maturation; Cerebral Disorders; Motor Disorders; Neurology.
English
2017
29
2
95
104
reserved
Cavanna, A., Black, K., Hallett, M., Voon, V. (2017). Neurobiology of the premonitory urge in Tourette syndrome: Pathophysiology and treatment implications. THE JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES, 29(2), 95-104 [10.1176/appi.neuropsych.16070141].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/401595
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