Introduction: Specific pre-existing medical conditions (e.g. hypertension or obesity), advanced age and male sex appear linked to more severe manifestations of SARS Co-V2 infection, thus raising the question of whether Parkinson's disease (PD) poses an increased risk of morbidity and mortality in COVID-19 patients. Methods: In order to describe the outcome of COVID-19 in multi-centre a cohort of PD patients and explore its potential predictors, we gathered the clinical information of 117 community-dwelling patients with COVID-19 followed in 21 tertiary centres in Italy, Iran, Spain, and the UK. Results: Overall mortality was 19.7%, with a significant effect of co-occurrence of dementia, hypertension, and PD duration. Conclusions: The frailty caused by advanced PD poses an increased risk of mortality during COVID-19.

Fasano, A., Elia, A., Dallocchio, C., Canesi, M., Alimonti, D., Sorbera, C., et al. (2020). Predictors of COVID-19 outcome in Parkinson's disease. PARKINSONISM & RELATED DISORDERS, 78, 134-137 [10.1016/j.parkreldis.2020.08.012].

Predictors of COVID-19 outcome in Parkinson's disease

Alimonti, Dario;
2020

Abstract

Introduction: Specific pre-existing medical conditions (e.g. hypertension or obesity), advanced age and male sex appear linked to more severe manifestations of SARS Co-V2 infection, thus raising the question of whether Parkinson's disease (PD) poses an increased risk of morbidity and mortality in COVID-19 patients. Methods: In order to describe the outcome of COVID-19 in multi-centre a cohort of PD patients and explore its potential predictors, we gathered the clinical information of 117 community-dwelling patients with COVID-19 followed in 21 tertiary centres in Italy, Iran, Spain, and the UK. Results: Overall mortality was 19.7%, with a significant effect of co-occurrence of dementia, hypertension, and PD duration. Conclusions: The frailty caused by advanced PD poses an increased risk of mortality during COVID-19.
Articolo in rivista - Articolo scientifico
COVID-19; Dementia; Outcome; Parkinson's disease;
English
2020
78
134
137
none
Fasano, A., Elia, A., Dallocchio, C., Canesi, M., Alimonti, D., Sorbera, C., et al. (2020). Predictors of COVID-19 outcome in Parkinson's disease. PARKINSONISM & RELATED DISORDERS, 78, 134-137 [10.1016/j.parkreldis.2020.08.012].
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/394595
Citazioni
  • Scopus 61
  • ???jsp.display-item.citation.isi??? 60
Social impact