The use of carbohydrates as structural scaffolds for the design and synthesis of new drugs has found growing interest in the last decade. The main drawback of existing syntheses of carbohydrate scaffolds is the tedious protecting group manipulation necessary for the introduction of orthogonality of protecting groups. In this chapter, we describe a direct approach for generation of monocyclic and bicyclic C-galactosyl compounds from commercially available methyl α-d-galactopyranoside without the use of protecting groups.

La Ferla, B., Hogendorf, W., Nicotra, F., Cipolla, L. (2016). C-Glycosylation Starting from Unprotected O-Glycosides. In Pavol Kováč (a cura di), Carbohydrate Chemistry: Proven Synthetic Methods (pp. 83-89). CRC Press [10.1201/b11261-14].

C-Glycosylation Starting from Unprotected O-Glycosides

La Ferla, B;Cipolla, L
2016

Abstract

The use of carbohydrates as structural scaffolds for the design and synthesis of new drugs has found growing interest in the last decade. The main drawback of existing syntheses of carbohydrate scaffolds is the tedious protecting group manipulation necessary for the introduction of orthogonality of protecting groups. In this chapter, we describe a direct approach for generation of monocyclic and bicyclic C-galactosyl compounds from commercially available methyl α-d-galactopyranoside without the use of protecting groups.
Si
Scientifica
Capitolo o saggio
carbohydrates;
English
Carbohydrate Chemistry: Proven Synthetic Methods
9781439866894
eBook ISBN 9781439866931
La Ferla, B., Hogendorf, W., Nicotra, F., Cipolla, L. (2016). C-Glycosylation Starting from Unprotected O-Glycosides. In Pavol Kováč (a cura di), Carbohydrate Chemistry: Proven Synthetic Methods (pp. 83-89). CRC Press [10.1201/b11261-14].
La Ferla, B; Hogendorf, W; Nicotra, F; Cipolla, L
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10281/392271
Citazioni
  • Scopus 0
  • ???jsp.display-item.citation.isi??? ND
Social impact