Chronic activation of the renin-angiotensin system (RAS) plays an important role in the pathogenesis of heart failure. Increasing evidence indicates that other than the circulating RAS, a local RAS exists in several tissues, including the heart. The present study was carried out to quantify cardiac, renal, and pulmonary mRNA levels of renin, angiotensin-converting enzyme (ACE), and types 1 and 2 angiotensin II receptors (AT-1 and AT-2), in rats with different severities of heart failure.
Pieruzzi, F., Abassi, Z., & Keiser, H. (1995). Expression of renin-angiotensin system components in the heart, kidneys, and lungs of rats with experimental heart failure. CIRCULATION, 92(10), 3105-12.
Citazione: | Pieruzzi, F., Abassi, Z., & Keiser, H. (1995). Expression of renin-angiotensin system components in the heart, kidneys, and lungs of rats with experimental heart failure. CIRCULATION, 92(10), 3105-12. | |
Tipo: | Articolo in rivista - Articolo scientifico | |
Carattere della pubblicazione: | Scientifica | |
Titolo: | Expression of renin-angiotensin system components in the heart, kidneys, and lungs of rats with experimental heart failure | |
Autori: | Pieruzzi, F; Abassi, Z; Keiser, H | |
Autori: | ||
Data di pubblicazione: | 15-nov-1995 | |
Lingua: | English | |
Rivista: | CIRCULATION | |
Appare nelle tipologie: | 01 - Articolo su rivista |