PURPOSE OF REVIEW: Sex cord-stromal tumours (SCSTs) are rare ovarian cancers. As in the literature, only small case series or case reports are published, gathering solid evidence about their management is challenging. Surgery plays a pivotal role, and accurate staging is one of the most important prognostic factors. This review focuses on the current evidence for surgical staging in the management of SCSTs. RECENT FINDINGS: Staging procedures have been inferred by epithelial ovarian cancers; however, they are often only partially performed, and most SCSTs therefore end up incompletely staged, raising the issue of the need for restaging or further treatments. In addition, some parts of the staging procedure have been questioned over the years, and lymphadenectomy is now considered unnecessary for SCSTs.The generally favourable prognosis of SCSTs, the introduction of minimally invasive surgery and fertility-sparing approaches is empowering the question of which staging procedures are beneficial for these patients. We reviewed the role of each staging procedure proposed by the guidelines in light of new scientific updates. SUMMARY: Surgical staging should always be performed. It includes peritoneal samplings (peritoneal washing, multiple peritoneal biopsies, omental biopsy and biopsy of any suspicious area), whereas lymphadenectomy could be omitted. Laparoscopy may be considered a feasible approach.

Negri, S., Grassi, T., Fruscio, R. (2022). Use of staging for sex cord stromal tumours. CURRENT OPINION IN ONCOLOGY, 34(5 (September 2022)), 504-510 [10.1097/CCO.0000000000000860].

Use of staging for sex cord stromal tumours

Negri, Serena;Grassi, Tommaso;Fruscio, Robert
2022

Abstract

PURPOSE OF REVIEW: Sex cord-stromal tumours (SCSTs) are rare ovarian cancers. As in the literature, only small case series or case reports are published, gathering solid evidence about their management is challenging. Surgery plays a pivotal role, and accurate staging is one of the most important prognostic factors. This review focuses on the current evidence for surgical staging in the management of SCSTs. RECENT FINDINGS: Staging procedures have been inferred by epithelial ovarian cancers; however, they are often only partially performed, and most SCSTs therefore end up incompletely staged, raising the issue of the need for restaging or further treatments. In addition, some parts of the staging procedure have been questioned over the years, and lymphadenectomy is now considered unnecessary for SCSTs.The generally favourable prognosis of SCSTs, the introduction of minimally invasive surgery and fertility-sparing approaches is empowering the question of which staging procedures are beneficial for these patients. We reviewed the role of each staging procedure proposed by the guidelines in light of new scientific updates. SUMMARY: Surgical staging should always be performed. It includes peritoneal samplings (peritoneal washing, multiple peritoneal biopsies, omental biopsy and biopsy of any suspicious area), whereas lymphadenectomy could be omitted. Laparoscopy may be considered a feasible approach.
No
Articolo in rivista - Articolo scientifico
Scientifica
Carcinoma, Ovarian Epithelial; Female; Humans; Lymph Node Excision; Neoplasm Staging; Prognosis; Ovarian Neoplasms; Sex Cord-Gonadal Stromal Tumors
English
504
510
7
Negri, S., Grassi, T., Fruscio, R. (2022). Use of staging for sex cord stromal tumours. CURRENT OPINION IN ONCOLOGY, 34(5 (September 2022)), 504-510 [10.1097/CCO.0000000000000860].
Negri, S; Grassi, T; Fruscio, R
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10281/390866
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