A new generation of quasimonochromatic high-flux X-ray sources, based on the X-ray radiation produced through Compton scattering between an electron beam and a laser beam, is under development. One of the possible applications of this source is inline phase contrast mammography, based on the observation of the edge-enhancement effect that can be observed at the border of structures inside the breast in images produced using a partially or totally coherent X-ray beam. In this work we present the results of a set of simulations of inline phase contrast mammography using typical inverse Compton scattering sources parameters. The simulated sample was a tumour-like mass having spherical shape, diameter between 200 μm and 5 mm, placed inside a breast-like matrix, 4 cm thick, and a standard composition of 50% glandular tissue and 50% adipose tissue. We discuss the minimum requirements for mammography using inverse Compton scattering sources and we discuss how the working parameters of the experimental setup (focal spot size, source-object distance, object-detector distance, detector point spread function, mean energy, energy bandwidth) affect the image quality, and specifically the edge-enhancement visibility. In particular, we show that the energy bandwidth does not significantly affect the visibility up to several keV. On the other hand, the edge-enhancement visibility depends substantially on other parameters such as source-object distance and detector point spread function.

Golosio, B., Delogu, P., Zanette, I., Oliva, P., Stefanini, A., Stegel, G., et al. (2009). Visibility of tumor-like details in inline phase contrast mammography using quasimonochromatic X-ray sources. NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH. SECTION A, ACCELERATORS, SPECTROMETERS, DETECTORS AND ASSOCIATED EQUIPMENT, 608(1S), 66-69 [10.1016/j.nima.2009.05.037].

Visibility of tumor-like details in inline phase contrast mammography using quasimonochromatic X-ray sources

CARPINELLI, Massimo
2009

Abstract

A new generation of quasimonochromatic high-flux X-ray sources, based on the X-ray radiation produced through Compton scattering between an electron beam and a laser beam, is under development. One of the possible applications of this source is inline phase contrast mammography, based on the observation of the edge-enhancement effect that can be observed at the border of structures inside the breast in images produced using a partially or totally coherent X-ray beam. In this work we present the results of a set of simulations of inline phase contrast mammography using typical inverse Compton scattering sources parameters. The simulated sample was a tumour-like mass having spherical shape, diameter between 200 μm and 5 mm, placed inside a breast-like matrix, 4 cm thick, and a standard composition of 50% glandular tissue and 50% adipose tissue. We discuss the minimum requirements for mammography using inverse Compton scattering sources and we discuss how the working parameters of the experimental setup (focal spot size, source-object distance, object-detector distance, detector point spread function, mean energy, energy bandwidth) affect the image quality, and specifically the edge-enhancement visibility. In particular, we show that the energy bandwidth does not significantly affect the visibility up to several keV. On the other hand, the edge-enhancement visibility depends substantially on other parameters such as source-object distance and detector point spread function.
Articolo in rivista - Articolo scientifico
Scientifica
Compact X-ray sources; Inverse Compton scattering; X-ray phase contrast imaging;
English
Golosio, B., Delogu, P., Zanette, I., Oliva, P., Stefanini, A., Stegel, G., et al. (2009). Visibility of tumor-like details in inline phase contrast mammography using quasimonochromatic X-ray sources. NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH. SECTION A, ACCELERATORS, SPECTROMETERS, DETECTORS AND ASSOCIATED EQUIPMENT, 608(1S), 66-69 [10.1016/j.nima.2009.05.037].
Golosio, B; Delogu, P; Zanette, I; Oliva, P; Stefanini, A; Stegel, G; Carpinelli, M
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10281/389386
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