A prototype of proton Computed Tomography (pCT) system for hadron-therapy has been manufactured and tested in a 175 MeV proton beam with a non-homogeneous phantom designed to simulate high-contrast material. BI-SART reconstruction algorithms have been implemented with GPU parallelism, taking into account of most likely paths of protons in matter. Reconstructed tomography images with density resolutions r.m.s. down to ~1% and spatial resolutions <1 mm, achieved within processing times of ~15′ for a 512×512 pixels image prove that this technique will be beneficial if used instead of X-CT in hadron-therapy.
Bruzzi, M., Civinini, C., Scaringella, M., Bonanno, D., Brianzi, M., Carpinelli, M., et al. (2017). Proton computed tomography images with algebraic reconstruction. NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH. SECTION A, ACCELERATORS, SPECTROMETERS, DETECTORS AND ASSOCIATED EQUIPMENT, 845, 652-655 [10.1016/j.nima.2016.05.056].