Five patients with neuropathy and IgM M-proteins that reacted with myelin-associated glycoprotein (MAG) were treated for 10 to 20 months with cytostatic agents. In 2 patients, a decrease in serum M-protein and in anti-MAG IgM levels coincided with a progressive improvement of neuropathy. No clinical improvement and no decrease of anti-MAG IgM were observed in the other patients. The close relationship between the decrease of anti-MAG M-proteins and clinical improvement in these patients supports the pathogenetic role of the M-protein in the neuropathy

Nobile Orazio, E., Baldini, L., Barbieri, S., Marmiroli, P., Spagnol, G., Francomano, E., et al. (1988). Treatment of patients with neuropathy and anti-MAG IgM M-proteins. ANNALS OF NEUROLOGY, 24(1), 93-97 [10.1002/ana.410240118].

Treatment of patients with neuropathy and anti-MAG IgM M-proteins.

MARMIROLI, PAOLA LORENA;
1988

Abstract

Five patients with neuropathy and IgM M-proteins that reacted with myelin-associated glycoprotein (MAG) were treated for 10 to 20 months with cytostatic agents. In 2 patients, a decrease in serum M-protein and in anti-MAG IgM levels coincided with a progressive improvement of neuropathy. No clinical improvement and no decrease of anti-MAG IgM were observed in the other patients. The close relationship between the decrease of anti-MAG M-proteins and clinical improvement in these patients supports the pathogenetic role of the M-protein in the neuropathy
Articolo in rivista - Articolo scientifico
neuropathy; myelin-associated glycoprotein;
English
93
97
5
Nobile Orazio, E., Baldini, L., Barbieri, S., Marmiroli, P., Spagnol, G., Francomano, E., et al. (1988). Treatment of patients with neuropathy and anti-MAG IgM M-proteins. ANNALS OF NEUROLOGY, 24(1), 93-97 [10.1002/ana.410240118].
Nobile Orazio, E; Baldini, L; Barbieri, S; Marmiroli, P; Spagnol, G; Francomano, E; Scarlato, G
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/38903
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