Metachromatic leukodystrophy is a genetical disorder due to a deficiency of arylsulphatase A activity. According to the age of onset of symptoms three different forms of the disease are described: late infantile, juvenile and adult types. We report the clinical, neuroimaging, biochemical and morphological features in a man in which the first symptoms ensued at the age of 39. In this patient, whose clinical manifestations were represented by "psychiatric" symptoms, the onset was particularly late in comparison with the large majority of the previously reported cases.

Marmiroli, P., Cavaletti, G., Bertagnolio, B., Maccarini, B., Tredici, G. (1990). Neuropathological and enzymatic studies in a case of adult form of metachromatic leukodystrophy with very late onset of clinical symptoms. ACTA NEUROLOGICA, 12(3), 184-192.

Neuropathological and enzymatic studies in a case of adult form of metachromatic leukodystrophy with very late onset of clinical symptoms.

MARMIROLI, PAOLA LORENA;CAVALETTI, GUIDO ANGELO;TREDICI, GIOVANNI
1990

Abstract

Metachromatic leukodystrophy is a genetical disorder due to a deficiency of arylsulphatase A activity. According to the age of onset of symptoms three different forms of the disease are described: late infantile, juvenile and adult types. We report the clinical, neuroimaging, biochemical and morphological features in a man in which the first symptoms ensued at the age of 39. In this patient, whose clinical manifestations were represented by "psychiatric" symptoms, the onset was particularly late in comparison with the large majority of the previously reported cases.
Articolo in rivista - Articolo scientifico
metachromatic leukodystrophy; psychiatric symptoms;
English
184
192
9
Marmiroli, P., Cavaletti, G., Bertagnolio, B., Maccarini, B., Tredici, G. (1990). Neuropathological and enzymatic studies in a case of adult form of metachromatic leukodystrophy with very late onset of clinical symptoms. ACTA NEUROLOGICA, 12(3), 184-192.
Marmiroli, P; Cavaletti, G; Bertagnolio, B; Maccarini, B; Tredici, G
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/38898
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