Peripheral blood mononuclear cells (PBMCs) derived from a healthy 40-year-old female were successfully transformed into induced pluripotent stem cells (iPSCs) by using the integration-free CytoTune-iPS Sendai Reprogramming method. The resulting iPSCs line exhibits a normal karyotype, expresses stemness markers and displays the differentiation capacity into the three germ layers. This human iPSCs line can be used as healthy control in disease modelling studies.

Bono, F., Mutti, V., Piovani, G., Minelli, A., Mingardi, J., Guglielmi, A., et al. (2021). Establishment and characterization of induced pluripotent stem cell (iPSCs) line UNIBSi014-A from a healthy female donor. STEM CELL RESEARCH, 51(March 2021) [10.1016/j.scr.2021.102216].

Establishment and characterization of induced pluripotent stem cell (iPSCs) line UNIBSi014-A from a healthy female donor

Mingardi J.;
2021

Abstract

Peripheral blood mononuclear cells (PBMCs) derived from a healthy 40-year-old female were successfully transformed into induced pluripotent stem cells (iPSCs) by using the integration-free CytoTune-iPS Sendai Reprogramming method. The resulting iPSCs line exhibits a normal karyotype, expresses stemness markers and displays the differentiation capacity into the three germ layers. This human iPSCs line can be used as healthy control in disease modelling studies.
Articolo in rivista - Articolo scientifico
Adult; Cell Differentiation; Cellular Reprogramming; Female; Germ Layers; Humans; Induced Pluripotent Stem Cells; Leukocytes, Mononuclear;
English
Bono, F., Mutti, V., Piovani, G., Minelli, A., Mingardi, J., Guglielmi, A., et al. (2021). Establishment and characterization of induced pluripotent stem cell (iPSCs) line UNIBSi014-A from a healthy female donor. STEM CELL RESEARCH, 51(March 2021) [10.1016/j.scr.2021.102216].
Bono, F; Mutti, V; Piovani, G; Minelli, A; Mingardi, J; Guglielmi, A; Missale, C; Gennarelli, M; Fiorentini, C; Barbon, A
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/376691
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