Sacubritil ∗ valsartan (Entresto, Novartis, still commonly referred to as LCZ696) is a combination drug described as a new class of dual-acting angiotensin receptor–neprilysin inhibitor (ARNi). This combination drug has been successfully studied in patients with heart failure with both preserved (HFpEF) and reduced ejection fraction (HFrEF). In this review, the evidences in patients with HFpEF and HFrEF are summarized, including the results of more recent studies.

Gori, M., Volterrani, M., Piepoli, M., Senni, M. (2017). Angiotensin receptor-neprilysin inhibitor (ARNi): Clinical studies on a new class of drugs. INTERNATIONAL JOURNAL OF CARDIOLOGY, 226, 136-140 [10.1016/j.ijcard.2016.06.083].

Angiotensin receptor-neprilysin inhibitor (ARNi): Clinical studies on a new class of drugs

Senni M
2017

Abstract

Sacubritil ∗ valsartan (Entresto, Novartis, still commonly referred to as LCZ696) is a combination drug described as a new class of dual-acting angiotensin receptor–neprilysin inhibitor (ARNi). This combination drug has been successfully studied in patients with heart failure with both preserved (HFpEF) and reduced ejection fraction (HFrEF). In this review, the evidences in patients with HFpEF and HFrEF are summarized, including the results of more recent studies.
Articolo in rivista - Review Essay
Angiotensin receptor–neprilysin inhibitor; ARNi; Heart failure; LCZ696;
English
136
140
5
Gori, M., Volterrani, M., Piepoli, M., Senni, M. (2017). Angiotensin receptor-neprilysin inhibitor (ARNi): Clinical studies on a new class of drugs. INTERNATIONAL JOURNAL OF CARDIOLOGY, 226, 136-140 [10.1016/j.ijcard.2016.06.083].
Gori, M; Volterrani, M; Piepoli, M; Senni, M
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/372359
Citazioni
  • Scopus 8
  • ???jsp.display-item.citation.isi??? 8
Social impact