1. Experiments were carried out to investigate whether the activation of renal chemoceptive receptors by natural stimuli might induce reflex alterations of efferent postganglionic activity to the ipsilateral kidney and preganglionic activity to the ipsilateral adrenal. 2. In anaesthetized rats with intact nervous system back-flow of urine and occlusion of the renal artery were accompanied by increments in efferent sympathetic activity both to the kidney and adrenal without concomitant changes in heart rate and blood pressure. 3. Greater excitatory responses in nerve activity to the same test stimuli were observed in rats with the spinal cord cut at C 1. 4. These results indicate that the natural activation of renal chemoceptive receptors might induce reno-renal and reno-adrenal excitatory reflexes which are likely to be integrated at spinal and supraspinal levels.

Recordati, G., Genovesi, S., Cerati, D., di Cintio, R. (1980). Reno-renal and reno-adrenal reflexes in the rat. CLINICAL SCIENCE, 59(6 suppl), S323-S325 [10.1042/cs059323s].

Reno-renal and reno-adrenal reflexes in the rat

GENOVESI, SIMONETTA CARLA;
1980

Abstract

1. Experiments were carried out to investigate whether the activation of renal chemoceptive receptors by natural stimuli might induce reflex alterations of efferent postganglionic activity to the ipsilateral kidney and preganglionic activity to the ipsilateral adrenal. 2. In anaesthetized rats with intact nervous system back-flow of urine and occlusion of the renal artery were accompanied by increments in efferent sympathetic activity both to the kidney and adrenal without concomitant changes in heart rate and blood pressure. 3. Greater excitatory responses in nerve activity to the same test stimuli were observed in rats with the spinal cord cut at C 1. 4. These results indicate that the natural activation of renal chemoceptive receptors might induce reno-renal and reno-adrenal excitatory reflexes which are likely to be integrated at spinal and supraspinal levels.
Articolo in rivista - Articolo scientifico
Chemoreceptor Cells; Animals; Sympathetic Nervous System; Blood Pressure; Vagotomy; Neurons, Efferent; Kidney Pelvis; Denervation; Rats; Heart Rate; Adrenal Glands; Kidney; Reflex; Male
English
1980
59
6 suppl
S323
S325
none
Recordati, G., Genovesi, S., Cerati, D., di Cintio, R. (1980). Reno-renal and reno-adrenal reflexes in the rat. CLINICAL SCIENCE, 59(6 suppl), S323-S325 [10.1042/cs059323s].
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/36411
Citazioni
  • Scopus 12
  • ???jsp.display-item.citation.isi??? 12
Social impact