Introduction. This study aimed to estimate the incidence of SARS-CoV-2 infection among pregnant women during the first pandemic wave in Italy, and to describe CO-VID-19 disease characteristics and maternal and perinatal outcomes. Materials and methods. National population-based prospective cohort study collecting information on women with SARS-CoV-2 diagnosis, confirmed within 7 days from hospital admission. Results. The national SARS-CoV-2 rate was 6.04 per 1,000 births (95% CI 5.62-6.49) among pregnant women and 7.54 (95% CI 7.47-7.61) among women in reproductive age. 72.1% of the cohort developed mild COVID-19 disease without pneumonia nor need for ventilatory support. Severe disease was significantly associated with women’s previous comorbidities (OR 2.55; 95% CI 0.98-6.90), obesity (OR 4.76; 95% CI 1.79-12.66) and citizenship from High Migration Pressure Countries (OR 3.43; 95% CI 1.27-9.25). Conclusions. During the first pandemic wave in Italy, the SARS-CoV-2 rate among pregnant women was lower compared to that detected among women of reproductive age, and risks of severe COVID-19 disease and adverse maternal and perinatal outcomes were rare.

Donati, S., Corsi, E., Maraschini, A., Salvatore, M., Baltaro, F., Boldrini, R., et al. (2021). The first SARS-CoV-2 wave among pregnant women in Italy: results from a prospective population-based study. ANNALI DELL'ISTITUTO SUPERIORE DI SANITÀ, 57(4), 272-285 [10.4415/ANN_21_04_02].

The first SARS-CoV-2 wave among pregnant women in Italy: results from a prospective population-based study

Tironi R.;Vergani P.
2021

Abstract

Introduction. This study aimed to estimate the incidence of SARS-CoV-2 infection among pregnant women during the first pandemic wave in Italy, and to describe CO-VID-19 disease characteristics and maternal and perinatal outcomes. Materials and methods. National population-based prospective cohort study collecting information on women with SARS-CoV-2 diagnosis, confirmed within 7 days from hospital admission. Results. The national SARS-CoV-2 rate was 6.04 per 1,000 births (95% CI 5.62-6.49) among pregnant women and 7.54 (95% CI 7.47-7.61) among women in reproductive age. 72.1% of the cohort developed mild COVID-19 disease without pneumonia nor need for ventilatory support. Severe disease was significantly associated with women’s previous comorbidities (OR 2.55; 95% CI 0.98-6.90), obesity (OR 4.76; 95% CI 1.79-12.66) and citizenship from High Migration Pressure Countries (OR 3.43; 95% CI 1.27-9.25). Conclusions. During the first pandemic wave in Italy, the SARS-CoV-2 rate among pregnant women was lower compared to that detected among women of reproductive age, and risks of severe COVID-19 disease and adverse maternal and perinatal outcomes were rare.
Articolo in rivista - Articolo scientifico
Cohort studies; Italy; Pregnancy outcome; SARS-CoV-2;
English
272
285
14
Donati, S., Corsi, E., Maraschini, A., Salvatore, M., Baltaro, F., Boldrini, R., et al. (2021). The first SARS-CoV-2 wave among pregnant women in Italy: results from a prospective population-based study. ANNALI DELL'ISTITUTO SUPERIORE DI SANITÀ, 57(4), 272-285 [10.4415/ANN_21_04_02].
Donati, S; Corsi, E; Maraschini, A; Salvatore, M; Baltaro, F; Boldrini, R; Bonassisa, S; Brunelli, R; Cagnacci, A; Casucci, P; Cataneo, I; Cetin, I; de Ambrosi, E; Manso, M; Fabiani, M; Fieni, S; Franchi, M; Iurlaro, E; Leo, L; Liberati, M; Sacchi, L; Livio, S; Locci, M; Marozio, L; Martini, C; Maso, G; Mecacci, F; Meloni, A; Mignuoli, A; Moresi, S; Patane, L; Perotti, F; Perrone, E; Prefumo, F; Ramenghi, L; Rusciani, R; Savasi, V; Schettini, S; Simeone, D; Soligo, M; Steinkasserer, M; Tateo, S; Ternelli, G; Tironi, R; Trojano, V; Vergani, P
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/363783
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