We have studied the formation of Drosophila mushroom bodies using enhancer detector techniques to visualize specific components of these complex intrinsic brain structures. During embryogenesis, neuronal proliferation begins in four mushroom body neuroblasts and the major axonal pathways of the mushroom bodies are pioneered. During larval development, neuronal proliferation continues and further axonal projections in the pedunculus and lobes are formed in a highly structured manner characterized by spatial heterogeneity of reporter gene expression. Enhancer detector analysis identifies many genomic locations that are specifically activated in mushroom body intrinsic neurons (Kenyon cells) during the transition from embryonic to postembryonic development and during metamorphosis.

Tettamanti, M., Armstrong, J., Endo, ., Kaiser, K., & Reichert, H. (1997). Early development of the Drosophila mushroom bodies, brain centres for associative learning and memory. DEVELOPMENT GENES AND EVOLUTION, 207(4), 242-252 [10.1007/s004270050112].

Early development of the Drosophila mushroom bodies, brain centres for associative learning and memory

Tettamanti, M.;
1997

Abstract

We have studied the formation of Drosophila mushroom bodies using enhancer detector techniques to visualize specific components of these complex intrinsic brain structures. During embryogenesis, neuronal proliferation begins in four mushroom body neuroblasts and the major axonal pathways of the mushroom bodies are pioneered. During larval development, neuronal proliferation continues and further axonal projections in the pedunculus and lobes are formed in a highly structured manner characterized by spatial heterogeneity of reporter gene expression. Enhancer detector analysis identifies many genomic locations that are specifically activated in mushroom body intrinsic neurons (Kenyon cells) during the transition from embryonic to postembryonic development and during metamorphosis.
Articolo in rivista - Articolo scientifico
Scientifica
Drosophila; Enhancer-trap; GAL4; Kenyon cells; Mushroom bodies;
English
Tettamanti, M., Armstrong, J., Endo, ., Kaiser, K., & Reichert, H. (1997). Early development of the Drosophila mushroom bodies, brain centres for associative learning and memory. DEVELOPMENT GENES AND EVOLUTION, 207(4), 242-252 [10.1007/s004270050112].
Tettamanti, M; Armstrong, J; Endo, (; Kaiser, K; Reichert, H
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10281/363014
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