The adverse cardiovascular consequences of high blood pressure (BP) not only depend on absolute BP values, but also on BP variability (BPV). Evidence has been provided that independently of mean BP levels, BP variations in the short- and long-term are associated with the development, progression and severity of cardiac, vascular and renal organ damage, and with an increased risk of CVevents and mortality. Alterations in BPV have also been shown to be predictive of the development and progression of renal damage, which is of relevance if considering that impaired renal function in a hypertensive patient constitutes a very potent predictor of future CV events and mortality even in treated subjects. This review will address whether antihypertensive treatment should target alterations in BPV, in addition to reducing absolute BP levels, in order to achieve the highest CV and renal protection in hypertensive and renal patients.

Parati, G., OCHOA MUNERA, J., & Bilo, G. (2012). Blood pressure variability, cardiovascular risk, and risk of renal disease progression. CURRENT HYPERTENSION REPORTS, 14, 421-431 [10.1007/s11906-012-0290-7].

Blood pressure variability, cardiovascular risk, and risk of renal disease progression.

PARATI, GIANFRANCO;OCHOA MUNERA, JUAN EUGENIO;BILO, GRZEGORZ
2012

Abstract

The adverse cardiovascular consequences of high blood pressure (BP) not only depend on absolute BP values, but also on BP variability (BPV). Evidence has been provided that independently of mean BP levels, BP variations in the short- and long-term are associated with the development, progression and severity of cardiac, vascular and renal organ damage, and with an increased risk of CVevents and mortality. Alterations in BPV have also been shown to be predictive of the development and progression of renal damage, which is of relevance if considering that impaired renal function in a hypertensive patient constitutes a very potent predictor of future CV events and mortality even in treated subjects. This review will address whether antihypertensive treatment should target alterations in BPV, in addition to reducing absolute BP levels, in order to achieve the highest CV and renal protection in hypertensive and renal patients.
Articolo in rivista - Articolo scientifico
Scientifica
Hypertension, Blood pressure, BP, Short- and long-term BP variability, Cardiovascular risk, Cardiovascular morbidity and mortality, Renal disease, progression, End-stage renal disease, ESRD, Chronic kidney disease, CKD, Arterial hypertension, Ambulatory BP monitoring, Home BP monitoring, Antihypertensive treatment
English
Parati, G., OCHOA MUNERA, J., & Bilo, G. (2012). Blood pressure variability, cardiovascular risk, and risk of renal disease progression. CURRENT HYPERTENSION REPORTS, 14, 421-431 [10.1007/s11906-012-0290-7].
Parati, G; OCHOA MUNERA, J; Bilo, G
File in questo prodotto:
File Dimensione Formato  
Blood pressure variability-Curr Hypertens Rep 2012.pdf

Solo gestori archivio

Dimensione 286.5 kB
Formato Adobe PDF
286.5 kB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10281/36215
Citazioni
  • Scopus 87
  • ???jsp.display-item.citation.isi??? 84
Social impact