This trial was conducted to study the frequency of the slow acetylator phenotype in asymptomatic HIV patients having no previous reaction to sulfa- drugs, and to compare this frequency with the frequency found in healthy controls. Results show that HIV alone is not capable of modifying the acetylator phenotype; the prevalence of slow acetylator phenotype is the same in immune competent subjects and HIV-positive patients. It is more common in HIV-positive patients with a CD4+ lymphocyte count of less than 200 mm-3.

Quirino, T., Bonfanti, P., Arcidiacono, M., Pusterla, L., Cagni, A., Scaglione, F., et al. (1999). Acetylator phenotype prevalence in HIV-infected patients without previous trimethoprim-sulfamethoxazole hypersensitivity. BIOMÉDECINE & PHARMACOTHÉRAPIE, 53(5-6), 286-287 [10.1016/S0753-3322(99)80101-2].

Acetylator phenotype prevalence in HIV-infected patients without previous trimethoprim-sulfamethoxazole hypersensitivity

Bonfanti P.;
1999

Abstract

This trial was conducted to study the frequency of the slow acetylator phenotype in asymptomatic HIV patients having no previous reaction to sulfa- drugs, and to compare this frequency with the frequency found in healthy controls. Results show that HIV alone is not capable of modifying the acetylator phenotype; the prevalence of slow acetylator phenotype is the same in immune competent subjects and HIV-positive patients. It is more common in HIV-positive patients with a CD4+ lymphocyte count of less than 200 mm-3.
Articolo in rivista - Articolo scientifico
Acetylator phenotype; Drug hypersensitivity; HIV; Sulfa-drugs;
English
286
287
2
Quirino, T., Bonfanti, P., Arcidiacono, M., Pusterla, L., Cagni, A., Scaglione, F., et al. (1999). Acetylator phenotype prevalence in HIV-infected patients without previous trimethoprim-sulfamethoxazole hypersensitivity. BIOMÉDECINE & PHARMACOTHÉRAPIE, 53(5-6), 286-287 [10.1016/S0753-3322(99)80101-2].
Quirino, T; Bonfanti, P; Arcidiacono, M; Pusterla, L; Cagni, A; Scaglione, F; Milazzo, F
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/360978
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