A theoretical model for studying RNA base pairing is presented, based on similarity measures of the bases and corresponding indexes. Similarity calculations are made by evaluating atomic importance in molecules, a method that uses an original method for the calculation of electronic energy. The application of the model to both Watson-Crick and non-Watson-Crick pairings is commented on. Some theoretical considerations concerning the capability of the genetic code to repair dangerous mutations contribute to the ongoing debate. (C) 1996 Academic Press Limited
DI GENNARO, P., Sello, G., Termini, M. (1996). Analysis of a theoretical model based on similarity for studying RNA base pairings. JOURNAL OF THEORETICAL BIOLOGY, 181(4), 359-371 [10.1006/jtbi.1996.0137].
Analysis of a theoretical model based on similarity for studying RNA base pairings
DI GENNARO, PATRIZIA;
1996
Abstract
A theoretical model for studying RNA base pairing is presented, based on similarity measures of the bases and corresponding indexes. Similarity calculations are made by evaluating atomic importance in molecules, a method that uses an original method for the calculation of electronic energy. The application of the model to both Watson-Crick and non-Watson-Crick pairings is commented on. Some theoretical considerations concerning the capability of the genetic code to repair dangerous mutations contribute to the ongoing debate. (C) 1996 Academic Press Limited
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