The effects of fentonium were compared with those of placebo in a double-blind, cross-over trial involving 28 incontinent women with unstable bladder. Fentonium bromide proved significantly more effective in reducing urgency and urge incontinence (p less than 0.05), in reducing detrusor pressure rise during bladder filling (p less than 0.01) and in increasing bladder volume at first stimulus (p less than 0.05). Well tolerated, fentonium bromide proved useful in the treatment of unstable bladder.

Milani, R., Merlo, E., Scalambrino, S., Viganò, R. (1986). A double-blind trial of fentonium bromide in the treatment of incontinent unstable bladder. INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY THERAPY AND TOXICOLOGY, 24(8), 421-424.

A double-blind trial of fentonium bromide in the treatment of incontinent unstable bladder

MILANI, RODOLFO;
1986

Abstract

The effects of fentonium were compared with those of placebo in a double-blind, cross-over trial involving 28 incontinent women with unstable bladder. Fentonium bromide proved significantly more effective in reducing urgency and urge incontinence (p less than 0.05), in reducing detrusor pressure rise during bladder filling (p less than 0.01) and in increasing bladder volume at first stimulus (p less than 0.05). Well tolerated, fentonium bromide proved useful in the treatment of unstable bladder.
Articolo in rivista - Articolo scientifico
Atropine Derivatives; Parasympatholytics; Urinary Incontinence, Stress; Double-Blind Method; Humans; Adult; Clinical Trials as Topic; Aged; Urinary Incontinence; Middle Aged; Female
English
1986
24
8
421
424
none
Milani, R., Merlo, E., Scalambrino, S., Viganò, R. (1986). A double-blind trial of fentonium bromide in the treatment of incontinent unstable bladder. INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY THERAPY AND TOXICOLOGY, 24(8), 421-424.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/35903
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