Airborne particulate (PM) components from fossil fuel combustion can induce oxidative stress initiated by reactive oxygen species (ROS) that are strongly correlated with airway inflammation and asthma. A valid biomarker of airway inflammation is fractionated exhaled nitric oxide (FENO). The oxidative potential of PM2.5 can be evaluated with the dithiothreitol (DTT) dosage, which represents both ROS chemically produced and intracellular ROS of macrophages. This correlates with quality indicators of the internal environment and ventilation strategies such as dilution and removal of airborne contaminants.

Traina, G., Bolzacchini, E., Bonini, M., Contini, D., Mantecca, P., Caimmi, S., et al. (2022). Role of air pollutants mediated oxidative stress in respiratory diseases. PEDIATRIC ALLERGY AND IMMUNOLOGY, 33(27), 38-40 [10.1111/pai.13625].

Role of air pollutants mediated oxidative stress in respiratory diseases

Traina G.;Bolzacchini E.;Bonini M.;Contini D.;Mantecca P.
Membro del Collaboration Group
;
2022

Abstract

Airborne particulate (PM) components from fossil fuel combustion can induce oxidative stress initiated by reactive oxygen species (ROS) that are strongly correlated with airway inflammation and asthma. A valid biomarker of airway inflammation is fractionated exhaled nitric oxide (FENO). The oxidative potential of PM2.5 can be evaluated with the dithiothreitol (DTT) dosage, which represents both ROS chemically produced and intracellular ROS of macrophages. This correlates with quality indicators of the internal environment and ventilation strategies such as dilution and removal of airborne contaminants.
No
Articolo in rivista - Articolo scientifico
Scientifica
asthma; fractionated exhaled nitric oxide; indoor air quality; oxidative stress; particulate air pollution;
English
38
40
3
Traina, G., Bolzacchini, E., Bonini, M., Contini, D., Mantecca, P., Caimmi, S., et al. (2022). Role of air pollutants mediated oxidative stress in respiratory diseases. PEDIATRIC ALLERGY AND IMMUNOLOGY, 33(27), 38-40 [10.1111/pai.13625].
Traina, G; Bolzacchini, E; Bonini, M; Contini, D; Mantecca, P; Caimmi, S; Licari, A
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10281/355490
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