The major concern in transplanting patients with alcoholic liver disease (ALD) is the high rate of alcohol recidivism. Our aim was to assess the long-term outcome of liver transplantation (OLT) in a group of ALD patients in terms of post-OLT alcohol recidivism and its relationship with pre-OLT psychosocial variables and medical follow up. Fifty-one ALD patients underwent strict medical and psychosocial evaluation before and after OLT. Alcohol abuse was recorded in 60% and alcohol dependence in 40% of patients before OLT. The 5-year survival was similar to the one observed in non-ALD transplanted patients (64 vs 56%). Alcohol recidivism was observed in 33% of transplanted patients, 64% of whom were occasional and 36% were heavy drinkers. The admission of alcoholism by the patient and his/her family prior to OLT significantly predicted abstinence after OLT. A multidisciplinary approach evaluating medical and psycho-social variables before OLT and a close follow up after OLT are mandatory for ALD patients.

Burra, P., Mioni, D., Cillo, U., Fagiuoli, S., Senzolo, M., Naccarato, R., et al. (2000). Long-term medical and psycho-social evaluation of patients undergoing orthotopic liver transplantation for alcoholic liver disease. TRANSPLANT INTERNATIONAL, 13(suppl 1), S174-S178 [10.1007/s001470050320].

Long-term medical and psycho-social evaluation of patients undergoing orthotopic liver transplantation for alcoholic liver disease

FAGIUOLI S;
2000

Abstract

The major concern in transplanting patients with alcoholic liver disease (ALD) is the high rate of alcohol recidivism. Our aim was to assess the long-term outcome of liver transplantation (OLT) in a group of ALD patients in terms of post-OLT alcohol recidivism and its relationship with pre-OLT psychosocial variables and medical follow up. Fifty-one ALD patients underwent strict medical and psychosocial evaluation before and after OLT. Alcohol abuse was recorded in 60% and alcohol dependence in 40% of patients before OLT. The 5-year survival was similar to the one observed in non-ALD transplanted patients (64 vs 56%). Alcohol recidivism was observed in 33% of transplanted patients, 64% of whom were occasional and 36% were heavy drinkers. The admission of alcoholism by the patient and his/her family prior to OLT significantly predicted abstinence after OLT. A multidisciplinary approach evaluating medical and psycho-social variables before OLT and a close follow up after OLT are mandatory for ALD patients.
Articolo in rivista - Articolo scientifico
psycho-social evaluation; orthotopic liver transplantation; alcoholic liver disease;
English
S174
S178
Burra, P., Mioni, D., Cillo, U., Fagiuoli, S., Senzolo, M., Naccarato, R., et al. (2000). Long-term medical and psycho-social evaluation of patients undergoing orthotopic liver transplantation for alcoholic liver disease. TRANSPLANT INTERNATIONAL, 13(suppl 1), S174-S178 [10.1007/s001470050320].
Burra, P; Mioni, D; Cillo, U; Fagiuoli, S; Senzolo, M; Naccarato, R; Martines, D
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/354059
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