Sneddon syndrome is a non-inflammatory, non-atherosclerotic disease involving small and medium-sized arteries of the brain and of the skin. The arteriographic examination is often negative despite progressive impairment of the neurological status. In 3 patients with Sneddon syndrome cerebral perfusion was assessed with single photon emission computerized tomography (SPECT) and technetium99 m-hexamethylpropylenamineoxime (Tc99 HM PAO). A correlation between clinical and SPECT finding was found, with significant focal reduction of regional cerebral blood flow (rCBF) in the two more severely affected patients
Canepari, C., Cappa, S., Perani, D., Riva, M., Sterzi, R., Fazio, F. (1991). Sneddon syndrome: cerebral perfusion studies by Tc99m HM-PAO and SPECT. ITALIAN JOURNAL OF NEUROLOGICAL SCIENCES, 12(1), 39-43 [10.1007/BF02337612].
Sneddon syndrome: cerebral perfusion studies by Tc99m HM-PAO and SPECT
FAZIO, FERRUCCIO
1991
Abstract
Sneddon syndrome is a non-inflammatory, non-atherosclerotic disease involving small and medium-sized arteries of the brain and of the skin. The arteriographic examination is often negative despite progressive impairment of the neurological status. In 3 patients with Sneddon syndrome cerebral perfusion was assessed with single photon emission computerized tomography (SPECT) and technetium99 m-hexamethylpropylenamineoxime (Tc99 HM PAO). A correlation between clinical and SPECT finding was found, with significant focal reduction of regional cerebral blood flow (rCBF) in the two more severely affected patients
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